Results 51 to 60 of about 97,090 (245)

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

N-ACETYL-β-D-GLUCOSAMINIDASE OF VIBRIO CHOLERAE

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Study N-acetyl-β-D-glucosaminidase (chitobiase) (EC 3.2.1.30) in strains of Vibrio cholerae of O1/non-O1 serogroups of various origin, that is a component of chitinolytic complex taking into account object of isolation and epidemiologic significance
O. V. Duvanova, B. N. Mishankin, A. S. Vodopianov, V. M. Sorokin   +3 more
doaj   +1 more source

Environmental prevalence of toxigenic Vibrio cholerae O1 in Bangladesh coincides with V. cholerae non-O1 non-O139 genetic variants which overproduce autoinducer-2.

PLoS ONE, 2021
Prevalence of toxigenic Vibrio cholerae O1 in aquatic reservoirs in Bangladesh apparently increases coinciding with the occurrence of seasonal cholera epidemics.
Iftekhar Bin Naser, Tushar Ahmed Shishir, Shah Nayeem Faruque, M Mozammel Hoque, Anamul Hasan, Shah M Faruque   +5 more
doaj   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Performance of o1 pro and GPT-4 in Self-Assessment Questions for Nephrology Board Renewal

Frontiers in Medicine
BackgroundLarge language models (LLMs) are increasingly evaluated in medical education and clinical decision support, but their performance in highly specialized fields, such as nephrology, is not well established.
Ryunosuke Noda, Chiaki Yuasa, Fumiya Kitano, Daisuke Ichikawa, Yugo Shibagaki   +4 more
doaj   +1 more source

Hybrid Vibrio cholerae El Tor Lacking SXT Identified as the Cause of a Cholera Outbreak in the Philippines

mBio, 2015
Cholera continues to be a global threat, with high rates of morbidity and mortality. In 2011, a cholera outbreak occurred in Palawan, Philippines, affecting more than 500 people, and 20 individuals died.
David C. Klinzing, Seon Young Choi, Nur A. Hasan, Ronald R. Matias, Enrique Tayag, Josefina Geronimo, Evan Skowronski, Shah M. Rashed, Kent Kawashima, C. Nicole Rosenzweig, Henry S. Gibbons, Brian C. Torres, Veni Liles, Alicia C. Alfon, Maria Luisa Juan, Filipinas F. Natividad, Thomas A. Cebula, Rita R. Colwell   +17 more
doaj   +1 more source

Two‐Dimensional Triferroics: From Fundamental Couplings to Multifunctional Applications

Advanced Science, EarlyView.
This graphic summarizes the three main types of currently reported 2D triferroic couplings. From the structural perspective, existing systems can be broadly classified into two categories, which exhibit distinct symmetry features and coupling behaviors. Beyond the lattice difference, a third type involves the interplay among ferroelectricity, magnetism,
Yang Li, Jialin Gong, Zhiqing Li
wiley   +1 more source

Safety and immunogenicity of a killed bivalent (O1 and O139) whole-cell oral cholera vaccine in adults and children in Vellore, South India.

PLoS ONE, 2019
This open-label study assessed the safety and immunogenicity of two doses (14 days apart) of an indigenously manufactured, killed, bivalent (Vibrio cholerae O1 and O139), whole-cell oral cholera vaccine (SHANCHOL; Shantha Biotechnics) in healthy adults ...
Venkata Raghava Mohan, Santosh Raj, Mandeep Singh Dhingra, Naveena Aloysia D'Cor, Ajit Pal Singh, Tarun Saluja, Deok Ryun Kim, Venkat Jayanth Midde, Yanghee Kim, Sridhar Vemula, Santhosh Kumar Narla, Binod Sah, Mohammad Ali   +12 more
doaj   +1 more source

Structural Insights Into Man9 Recognition by the HIV Antibody 2G12 Revealed by Paramagnetic NMR

Advanced Science, EarlyView.
The HIV gp120 glycoprotein displays Man9 oligomannose structures that are recognized by the neutralizing antibody 2G12. Detailed characterization of the binding epitope in solution is important for immunogen design but remains challenging, since the signals of the terminal mannoses from the three arms of Man9 (D1, D2, and D3) cannot be distinguished in
Adrián Silva‐Díaz, Paola Oquist‐Phillips, Noelia de la Cruz, Inés Lera‐Lasso, Laura Castañar, Javier Rojo, Javier Ramos‐Soriano, Ángeles Canales   +7 more
wiley   +1 more source