Results 141 to 150 of about 301,621 (273)

Inflammatory Mediators Both Directly and Indirectly Promote Microglial Proliferation

open access: yesGlia, Volume 74, Issue 5, May 2026.
– CSF2, IL3, and TNFɑ directly promote microglial proliferation. – Neuron‐secreted factors suppress microglial proliferation. – IL1 cytokines promote CSF2 release from astrocytes, which promotes microglial proliferation. ABSTRACT Microglia—the predominant immune cell of the central nervous system (CNS)—possess an astounding capacity for proliferation ...
Brady P. Hammond   +4 more
wiley   +1 more source

Elucidating the Stereodirecting Effect of C‐4 Acyl Groups on Galactosyl Donors

open access: yesAngewandte Chemie, Volume 138, Issue 14, 27 March 2026.
Tipping the balance of the reaction coordinate by changing a single protecting group. We demonstrate that α‐ and β‐galactosyl triflates are formed during galactosylation reactions and likely glycosylate according to a Curtin–Hammett scenario. C‐4 acyl groups exert their stereodirecting effect by sterically blocking displacement of α‐galactosyl ...
Floor ter Braak   +8 more
wiley   +2 more sources

Reduced dynamic model of the alternate arm converter [PDF]

open access: yes, 2014
Green, TC, Merlin, MMC, Sheridan, CE
core   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1057-1069, April 2026.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka   +12 more
wiley   +1 more source

catena-Poly[[diaquamanganese(II)]-μ-pyridine-2,4,6-tricarboxylato-κ5N,O2,O6:O4,O4′]

open access: yesActa Crystallographica Section E, 2008
In the title compound, [Mn(C8H2NO6)(H2O)2]n, each pyridine-2,4,6-tricarboxylate (tpc) ligand bridges two MnII ions with the formation of polymeric chains located on a twofold rotation axis. Each MnII ion is coordinated by two O and one N atoms from one tpc ligand, two O atoms from another ligand and two water molecules in a distorted pentagonal– ...
Da-Wei Fu, Hai-Jun Xu
openaire   +1 more source

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling   +9 more
wiley   +1 more source

Polarons in Heterogeneous Photo(electro)Catalysts

open access: yesAngewandte Chemie, Volume 138, Issue 13, 23 March 2026.
Polarons are defined as quasiparticles consisting of electrons/holes covered by a cloud of virtual phonons, which are beneficial/detrimental to the electronic properties of materials. This minireview provides a conceptual overview of how small polaron formation influences the photon absorption, charge transport and separation, and surface reactivity in
Hao Wu, Fatwa F. Abdi, Yun Hau Ng
wiley   +2 more sources

Machine Learning Model for an App‐Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 236-246, April 2026.
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Xavier Langon   +2 more
wiley   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes   +8 more
wiley   +1 more source

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