Results 121 to 130 of about 197,097 (210)

Scoping review of comminuted fractures of the proximal phalanx in horses

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 664-673, May 2026.
Abstract Background Comminuted fractures of the proximal phalanx (CFPP) occur in adult horses. Various treatments have been described. It remains uncertain which is the best therapeutic option. Objectives This study aims to review systematically the existing literature on CFPP in horses, evaluate treatment modalities, synthesise outcomes to assess ...
Charles de Chaisemartin   +2 more
wiley   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Designing Advanced Soft Magnetic Powder Cores with Ultralow Energy Loss by Combining Ultrasonic and Static Compaction

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
Increasing the density and homogeneity of soft magnetic composites are critical for achieving high power density and low core loss. This work proposes a novel strategy by combining ultrasonic‐assisted pressing and cold pressing. In this line, the density and permeability of magnetic core have been increased a lot, while the core loss is decreased ...
Xiaoying Huang   +15 more
wiley   +1 more source

Panacis Quinquefolii Radix Polysaccharides Alleviate Depressive‐Like Behaviors in Chronic Unpredictable Mild Stress‐Induced Mice by Suppressing Complement C1Q/C3‐Mediated Microglial Synaptic Pruning and Modulating Gut Microbiota

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
XYS1 ameliorates depressive‐like behaviors in CUMS mice via the gut‐brain axis by inhibiting complement activation, suppressing microglial phagocytosis, restoring gut microbiota, and alleviating inflammation. ABSTRACT Aims Panax quinquefolius Radix (American ginseng) is a medicinal herb used for its neuroprotective and tonic effects.
Mengjun Xie   +12 more
wiley   +1 more source

Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 483-489, April 2026.
The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand   +3 more
wiley   +1 more source

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