Results 11 to 20 of about 197,097 (210)

OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research [PDF]

, 2019
Online application for survival analysis (OASIS) has served as a popular and convenient platform for the statistical analysis of various survival data, particularly in the field of aging research.
Donghyo Kim, Dongyeop Lee, Heetak Lee, Jae-Seong Yang, Lee, SJV, Sanguk Kim, Seong Kyu Han, Son, HG   +7 more
core   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

A 60 pc counter-rotating core in NGC 4621

, 2002
We present adaptive optics assisted OASIS integral field spectrography of the S0 galaxy NGC 4621. Two-dimensional stellar kinematical maps (mean velocity and dispersion) reveal the presence of a 60 pc diameter counter-rotating core (CRC), the smallest ...
Bacon, Bacon, Bender, Bender, Bender, Byun, Carollo, Cole, de Zeeuw, de Zeeuw, E. Emsellem, Emsellem, F. Wernli, Faber, Hunter, Idiart, Lauer, Merritt, Merritt, Moellenhoff, Monnet, Richstone, Rieke, Rigaut, Tonry, van der Marel, Wagner, Y. Copin   +27 more
core   +3 more sources

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

The M 31 double nucleus probed with OASIS and HST. A natural m=1 mode? [PDF]

, 2001
We present observations with the adaptive optics assisted integral field spectrograph OASIS of the M 31 double nucleus at a spatial resolution better than 0.5 arcsec FWHM.
Bacon, Bacon, Bender, Brown, Davidge, del Burgo, Dressler, E. Emsellem, Emsellem, Emsellem, F. Combes, Ferrarese, G. Monnet, Gebhardt, Goldreich, Heemskerk, James, King, Kormendy, Kormendy, Lauer, Lauer, Lee, Levine, Light, Lovelace, Magorrian, Melchior, Merritt, Miller, Monnet, P. Martin, R. Bacon, Rigaut, Sambhus, Statler, Statler, Stephen, Taga, Tremaine, van der Marel, Weinberg, Y. Copin   +42 more
core   +3 more sources

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

Advanced Science, EarlyView.
In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu, Taiheng Ma, Qi Liu, He Zhu, Zheng Fang, Jiahong Ma, Ting Yu, Yan Wang, Jiahua Zhou, Xiaoyan Liu, Yaqian Li, Zhimou Guo, Xinmiao Liang, Mingming Dong, Deguang Sun, Mingliang Ye   +15 more
wiley   +1 more source

Biodiversity and distribution of cyanobacteria at Dronning Maud Land, East Antartica [PDF]

, 2008
Biodiversity and distribution of cyanobacteria at Dronning Maud Land, East Antarctica.The current study describes the biodiversity and distribution of cyanobacteria from the natural habitats of Schirmacher land, East Antarctica surveyed during 23rd ...
Singh, Purnima, Singh, Shiv Mohan, Thajuddin, Nooruddin   +2 more
core   +4 more sources

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Innovative public governance through cloud computing: Information privacy, business models and performance measurement challenges [PDF]

, 2014
Purpose: The purpose of this paper is to identify and analyze challenges and to discuss proposed solutions for innovative public governance through cloud computing.
Irani, Z, Lee, H, Tsohou, A
core   +1 more source