Results 221 to 230 of about 205,716 (289)

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, Volume 13, Issue 28, 18 May 2026.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Anexos

OASIS, 2005
Revista OASIS
doaj  

The OASIS Consortium: integrating multi-omics technologies to transform chemical safety assessment. [PDF]

Toxicol Sci
Rouquié D, Bender A, Cheah J, Crute CE, Dalmas D, Ewald J, Fullerton A, Harrill JA, Kadri S, Kleinstreuer N, Kramer N, LaRocca J, Mitchell CA, Seal S, Singh S, Carpenter AE.   +15 more
europepmc   +1 more source

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

Annals of Neurology, Volume 99, Issue 5, Page 1327-1342, May 2026.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey‐Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph N. Martins, Colin L. Masters, James D. Doecke, for the Alzheimer's Disease Neuroimaging Initiative   +29 more
wiley   +1 more source

Resúmenes-Abstracts

OASIS, 2011
Revista OASIS
doaj  

How reproducible are data-driven subtypes of Alzheimer's disease atrophy? [PDF]

J Alzheimers Dis
Prevot E, Shand C, for Alzheimer’s Disease Neuroimaging Initiative, Oxtoby N.   +3 more
europepmc   +1 more source

Integrated Assessment of Lipid Oxidation and Off‐Flavor Formation in Plant Protein Powders

Journal of the American Oil Chemists' Society, Volume 103, Issue 5, Page 371-386, May 2026.
Impact of residual lipids on oxylipin and off‐flavor formation in commercial plant proteins: A detailed analysis of precursor‐product relationships by GC‐FID, LC‐MS/MS, and GC‐MS. ABSTRACT The widespread adoption of plant proteins is hindered by their inherent off‐flavors, often linked to lipid oxidation products.
Fernanda Furlan Goncalves Dias, Wellington da Silva Oliveira, Stanislau Bogusz Junior, Ameer Y. Taha   +3 more
wiley   +1 more source

Presentación

OASIS, 2008
Revista OASIS
doaj  

Construction and validation of a prognostic nomogram for predicting short-term mortality in acute respiratory failure patients: a retrospective cohort study based on the MIMIC-IV database. [PDF]

BMC Pulm Med
Wang Y, Zhang H, Ma X, Yang W.
europepmc   +1 more source

Retinal Pathology and Synucleinopathy in the Visual Pathway of α‐Synuclein Preformed Fibril Mouse Model of Parkinson's Disease

Brain and Behavior, Volume 16, Issue 5, May 2026.
Schematic summary of visual electrophysiology and retinal and brain pathology. The diagram integrates PVEP abnormalities, retinal pathology, and brain pathology in PFF‐injected mice. Based on behavioral outcomes, the three groups were categorized as control, prodromal PD, and PD, corresponding to the PBS, 3‐month PFF (3 MPI), and 6‐month PFF (6 MPI ...
Qin Zhang, Xin‐Yi Qian, Tao Peng, Xiao‐Ou Hou, Zhen‐Yuan Ma, Jiang Huang, Li‐Fang Hu, Wei‐Feng Luo   +7 more
wiley   +1 more source