Results 61 to 70 of about 13,356 (173)

Integrated miRNA–mRNA Analysis Reveals Obesity‐Driven Regulatory Networks in Human Visceral Adipose Tissue With and Without Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5992-6008, July 2026.
ABSTRACT Aims Obesity is characterised by pathological alterations in visceral white adipose tissue (vWAT) that may contribute to the development of type 2 diabetes (T2D). While microRNAs (miRNAs) are key post‐transcriptional regulators, comprehensive human vWAT profiling across metabolic states remains limited.
Elsa Villa‐Fernández   +19 more
wiley   +1 more source

Impact of Bariatric Surgery on metabolic health in a Uruguayan cohort and the emerging predictive role of FSTL1

open access: yesScientific Reports
Obesity poses significant challenges, necessitating comprehensive strategies for effective intervention. Bariatric Surgery (BS) has emerged as a crucial therapeutic approach, demonstrating success in weight loss and comorbidity improvement.
Leonardo Santos   +12 more
doaj   +1 more source

Differences in Fat Depots, Cardiometabolic Risk Factors, and Insulin Resistance Between Active and Passive School Commuters

open access: yesPediatric Obesity, Volume 21, Issue 7, July 2026.
ABSTRACT Background Active commuting to and from school (ACS) is a feasible strategy to increase daily physical activity in children. Although ACS has been associated with favourable body composition and selected cardiometabolic markers, its association with specific ectopic fat depots remains unclear in paediatric populations.
David Rodriguez‐Sanchez   +6 more
wiley   +1 more source

Increased Brown Adipose Tissue Thermogenesis in Phenylketonuria

open access: yesMedComm, Volume 7, Issue 6, June 2026.
In phenylketonuria (PKU), elevated phenylalanine (Phe) increases hepatic fibroblast growth factor 21 (FGF21) and thyroid hormones, enhancing brown adipose tissue (BAT) thermogenesis in patients. Central FGF21 reproduces this phenotype in rodents via reduced hypothalamic AMP‐activated protein kinase (AMPK) activity in the ventromedial nucleus of the ...
Noemí López‐Rey   +18 more
wiley   +1 more source

Genome‐Wide DNA Methylation Changes Induced by High‐Fat Diet and Methyl Donor Supplementation in Female Lupus Models: An Exploratory Study

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
A high‐fat diet induces widespread DNA methylation changes in adipose tissue in lupus‐prone mice, while methyl‐donor supplementation (folic acid and vitamin B12) modulates inflammatory pathways, including IL‐17 signaling, in a diet‐dependent manner. ABSTRACT This exploratory study investigated the interactive effects of dietary fat content and methyl ...
Amanda Alves Ribeiro   +12 more
wiley   +1 more source

Real‐World Effectiveness and Safety of iGlarLixi in People With Type 2 Diabetes in LATAM Region: A Subanalysis of the SUCCESS Study

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Juan Manuel Arteaga‐Diaz   +4 more
wiley   +1 more source

Planetary Health Diet Adherence Improves Weight and Body Composition During Energy Restriction

open access: yesObesity, Volume 34, Issue 6, Page 1265-1276, June 2026.
ABSTRACT Objective Obesity management relies on energy restriction, yet the contribution of dietary quality to weight‐loss and body composition outcomes during hypocaloric interventions remains poorly characterized. This study evaluated whether adherence to the Planetary Health Diet (PHD), as a measure of diet quality, and its key components is ...
Paola Mogna‐Peláez   +13 more
wiley   +1 more source

Efficacy of an Online Weight Loss Program for Mexican Adults: Findings From a Randomized Controlled Trial

open access: yesObesity Science &Practice, Volume 12, Issue 3, June 2026.
ABSTRACT Background Obesity is a major public health crisis in Mexico. With internet usage rapidly increasing, digital health interventions present a clear opportunity for treating obesity. This study addressed a key gap in research by evaluating a web‐based Intensive Lifestyle Modification intervention adapted from the Diabetes Prevention Program for ...
Alma Lorena Ruelas Yanes   +7 more
wiley   +1 more source

ARGENTINE CONSENSUS OF METABOLIC SURGERY

open access: yesRevista de la Sociedad Argentina de Diabetes, 2015
Introduction: the worldwide pandemic increase of obesity and type 2 diabetes push us to choose therapeutic options to control metabolic parameters and decrease cardiovascular risk in this group of patients. Metabolic surgery became a useful tool added to
Marianela Aguirre Ackermann   +26 more
doaj   +1 more source

Advancing our understanding of valued living: An ecological momentary assessment of behavioral and experiential aspects of valued actions, well‐being, and emotional distress

open access: yesApplied Psychology: Health and Well-Being, Volume 18, Issue 3, June 2026.
Abstract Although engaging in valued actions is often positively related to mental health, this relationship is not always consistent at the daily level, suggesting that how valued actions are experienced is also important. We examined three valued action aspects (extent of engagement, awareness of engaging in valued actions, and perceived effort) and ...
Pedro Sarrión   +5 more
wiley   +1 more source

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