Results 61 to 70 of about 13,356 (173)
ABSTRACT Aims Obesity is characterised by pathological alterations in visceral white adipose tissue (vWAT) that may contribute to the development of type 2 diabetes (T2D). While microRNAs (miRNAs) are key post‐transcriptional regulators, comprehensive human vWAT profiling across metabolic states remains limited.
Elsa Villa‐Fernández +19 more
wiley +1 more source
Obesity poses significant challenges, necessitating comprehensive strategies for effective intervention. Bariatric Surgery (BS) has emerged as a crucial therapeutic approach, demonstrating success in weight loss and comorbidity improvement.
Leonardo Santos +12 more
doaj +1 more source
ABSTRACT Background Active commuting to and from school (ACS) is a feasible strategy to increase daily physical activity in children. Although ACS has been associated with favourable body composition and selected cardiometabolic markers, its association with specific ectopic fat depots remains unclear in paediatric populations.
David Rodriguez‐Sanchez +6 more
wiley +1 more source
Increased Brown Adipose Tissue Thermogenesis in Phenylketonuria
In phenylketonuria (PKU), elevated phenylalanine (Phe) increases hepatic fibroblast growth factor 21 (FGF21) and thyroid hormones, enhancing brown adipose tissue (BAT) thermogenesis in patients. Central FGF21 reproduces this phenotype in rodents via reduced hypothalamic AMP‐activated protein kinase (AMPK) activity in the ventromedial nucleus of the ...
Noemí López‐Rey +18 more
wiley +1 more source
A high‐fat diet induces widespread DNA methylation changes in adipose tissue in lupus‐prone mice, while methyl‐donor supplementation (folic acid and vitamin B12) modulates inflammatory pathways, including IL‐17 signaling, in a diet‐dependent manner. ABSTRACT This exploratory study investigated the interactive effects of dietary fat content and methyl ...
Amanda Alves Ribeiro +12 more
wiley +1 more source
Planetary Health Diet Adherence Improves Weight and Body Composition During Energy Restriction
ABSTRACT Objective Obesity management relies on energy restriction, yet the contribution of dietary quality to weight‐loss and body composition outcomes during hypocaloric interventions remains poorly characterized. This study evaluated whether adherence to the Planetary Health Diet (PHD), as a measure of diet quality, and its key components is ...
Paola Mogna‐Peláez +13 more
wiley +1 more source
ABSTRACT Background Obesity is a major public health crisis in Mexico. With internet usage rapidly increasing, digital health interventions present a clear opportunity for treating obesity. This study addressed a key gap in research by evaluating a web‐based Intensive Lifestyle Modification intervention adapted from the Diabetes Prevention Program for ...
Alma Lorena Ruelas Yanes +7 more
wiley +1 more source
ARGENTINE CONSENSUS OF METABOLIC SURGERY
Introduction: the worldwide pandemic increase of obesity and type 2 diabetes push us to choose therapeutic options to control metabolic parameters and decrease cardiovascular risk in this group of patients. Metabolic surgery became a useful tool added to
Marianela Aguirre Ackermann +26 more
doaj +1 more source
Abstract Although engaging in valued actions is often positively related to mental health, this relationship is not always consistent at the daily level, suggesting that how valued actions are experienced is also important. We examined three valued action aspects (extent of engagement, awareness of engaging in valued actions, and perceived effort) and ...
Pedro Sarrión +5 more
wiley +1 more source

