Results 81 to 90 of about 997,879 (305)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Obesity and the obesity paradox in abdominal aortic aneurysm

Frontiers in Endocrinology
Obesity, characterized by its complexity and heterogeneity, has emerged as a significant public health concern. Its association with increased incidence and mortality of cardiovascular diseases stems not only from its complications and comorbidities but also from the endocrine effects of adipose tissue.
Feng Lu, Feng Lu, Yong Lin, Yong Lin, Jianshun Zhou, Jianshun Zhou, Zhen Chen, Zhen Chen, Yingying Liu, Yingying Liu, Maolin Zhong, Maolin Zhong, Lifeng Wang, Lifeng Wang, Lifeng Wang   +14 more
openaire   +3 more sources

First Report of Uniparental Isodisomy of Chromosome 15 Revealing Angelman Syndrome and Microphthalmia Associated With a Novel Homozygous ALDH1A3 Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Paternal isodisomy of chromosome 15 (iUPD15) is a recognized cause of Angelman syndrome (AS), accounting for approximately 2%–5% of cases. Additionally, another recognized consequence of iUPD is the unmasking of autosomal recessive disorders. However, reports of recessive disorders resulting from iUPD15 remain scarce in the literature.
Gabriela Roldão Correia‐Costa, Joana Rosa Marques Prota, Antonia Paula Marques‐de‐Faria, Carlos Eduardo Steiner, Társis Paiva Vieira   +4 more
wiley   +1 more source

Abdominal Obesity and the Metabolic Syndrome

Annals of Medicine, 1992
Abdominal obesity in man is an integrated part of the Metabolic Syndrome, and is associated with a complex neuroendocrine disturbance. Its consequences for the metabolism of the periphery seems to be insulin resistance caused by a combination of a relative hypercortisolaemia and a relative deficiency of sex steroid hormones.
openaire   +2 more sources

Sarcopenic obesity and risk of cardiovascular disease and mortality: A population-based cohort study of older men [PDF]

, 2014
Objectives To examine associations between sarcopenia, obesity, and sarcopenic obesity and risk of cardiovascular disease (CVD) and all-cause mortality in older men. Design Prospective cohort study. Setting British Regional Heart Study.
Morris, RW, Richard W. Morris, Olia Papacosta, Whincup, Peter H, Whincup, PH, Lucy T. Lennon, Morris, Richard W, Papacosta, O, Janice L. Atkins, Atkins, Janice L, Wannamethee, S Goya, Peter H. Whincup, Lennon, Lucy T, S. Goya Wannamethee, Lennon, LT, Wannamethee, SG, Papacosta, Olia, Atkins, JL   +17 more
core   +1 more source

Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri, Alessandro Serretti, Marco Menchetti, Benedetta Vai, Francesco Benedetti, Lidia Fortaner‐Uyà, Concetta Crisafulli   +6 more
wiley   +1 more source

Prevalência e fatores associados à obesidade central em escolares de Santa Catarina [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2013.Objetivo: Estimar a prevalência e verificar os fatores sociodemográficos e de consumo alimentar ...
Feltrin, Gabriella Bettiol
core  

An Investigation of Sleep Macro‐ and Microarchitecture by APOE Genotype

Annals of Neurology, EarlyView.
Objectives Apolipoprotein E ε4 (APOE ε4), a robust genetic risk factor for Alzheimer's disease (AD) is associated with functional connectivity deficits and amyloid pathology in brain regions involved in sleep regulation. Thus, alterations in sleep architecture may be one pathway through which ε4 contributes to Alzheimer's disease vulnerability. However,
Gawon Cho, Anne Chen, Eunyoung Choi, Orfeu M. Buxton, Daniel Kay, Adam Mecca, Brienne Miner   +6 more
wiley   +1 more source

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

The Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen, Emma Sherratt, Philip Stott, Rachel Norris   +3 more
wiley   +1 more source

Self-reported disability in adults with severe obesity [PDF]

, 2011
Self-reported disability in performing daily life activities was assessed in adults with severe obesity (BMI ≥ 35 kg/m2) using the Health Assessment Questionnaire (HAQ).
N. Williams, Saravanan, Ponnusamy, Kyrou, Ioannis, R. Thomas, I. Kyrou, L. Halder, Osei-Assibey, G., S. Taheri, Thomas, R., Taheri, S., Williams, N., Halder, L., Saravanan, P., Kumar, Sudhesh, Williams, Nerys R., Kyrou, I., P. Saravanan, Halder, L. (Louise), S. Kumar, Kumar, S., G. Osei-Assibey   +20 more
core   +1 more source