Results 151 to 160 of about 2,007,139 (344)

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Decomposing Racial Disparities in Obesity Prevalence

, 2015
Chelsea R. Singleton, Olivia Affuso, Bisakha Sen   +2 more
openalex   +1 more source

Rectal administration of buttermilk processed with medicinal plants alters gut microbiome in obese individuals

, 2021
Sarika Mane, Kunal Dixit, Nidhi Lathwal, Dhiraj Dhotre, Priyadarshani Arvind Kadus, Yogesh S. Shouche, Supriya Bhalerao   +6 more
openalex   +2 more sources

Dietary pattern changes, obesity and excess body fat in adults of a Brazilian birth cohort [PDF]

, 2022
Stephanie Camila Ribeiro Silva Muniz, Marco Antônio Barbieri, Gabrielle Floriano Sanches, Soraia Pinheiro Machado Arruda, Antônio Augusto Moura da Sílva, Daniela Saes Sartorelli, Heloísa Bettiol   +6 more
openalex   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Increased oxidative stress in obesity and its impact on metabolic syndrome.

Journal of Clinical Investigation, 2004
S. Furukawa, T. Fujita, M. Shimabukuro, M. Iwaki, Yukio Yamada, Yoshimitsu Nakajima, O. Nakayama, M. Makishima, M. Matsuda, I. Shimomura   +9 more
semanticscholar   +1 more source

Biomechanics of stomach tissues and structure in patients with obesity

, 2020
Emanuele Luigi Carniel, Alice Albanese, Chiara Giulia Fontanella, Piero G. Pavan, Luca Prevedello, C. Salmaso, Silvia Todros, Ilaria Toniolo, Mirto Foletto   +8 more
openalex   +2 more sources

Obesity-related glomerulopathy in the presence of APOL1 risk alleles

, 2022
Ronald Valdez Imbert, Nang San Hti Lar Seng, Michael B. Stokes, Belinda Jim   +3 more
openalex   +2 more sources

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

Obesity induces a phenotypic switch in adipose tissue macrophage polarization.

Journal of Clinical Investigation, 2007
C. Lumeng, Jennifer L Bodzin, A. Saltiel
semanticscholar   +1 more source