Results 131 to 140 of about 1,339,496 (303)

Clinical problems caused by obesity [PDF]

open access: yes, 2010
Over the past few decades the incidence of obesity has doubled worldwide and current estimates classify more than 1.5 billion adults as overweight and at least 500 million of them as clinically obese, with body mass index (BMI) over 25 kg/m2 and 30 kg ...
Weickert, Martin O., Kyrou, Ioannis
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eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

open access: yesAdvanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao   +14 more
wiley   +1 more source

Prevalence of self-reported obesity among U.S. adults by race/ethnicity, state and territory, BRFSS, 2016-2018 [PDF]

open access: yes
The state and territory adult obesity prevalence by Race/Ethnicity in 2016-2018DNPAO State Obesity Prevalence Map 2011Publication date from document properties.2018-obesity-prevalence-map-race-ethnicity-508 ...

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m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang   +26 more
wiley   +1 more source

Pharmacalogical management of obesity

open access: yes, 2015
Obesity is now an epidemic. The whole world which includes the developed and developing countries is grappling with the adverse effects of obesity. The creation of anti- obesity drugs has been a gigantic stride in the combat against obesity.
Mbamali, Afoamakachukwu Adaeze
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FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li   +16 more
wiley   +1 more source

Childhood Obesity Intervention Studies: A Narrative Review and Guide for Investigators, Authors, Editors, Reviewers, Journalists, and Readers to Guard Against Exaggerated Effectiveness Claims

open access: yes, 2019
Being able to draw accurate conclusions from childhood obesity trials is important to make advances in reversing the obesity epidemic. However, obesity research sometimes is not conducted or reported to appropriate scientific standards. To constructively
Heymsfield, Steven B.   +17 more
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Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

DNPAO State Obesity Prevalence Map 2012-2014

open access: yes
Definitions\ue2\u20ac\ua2 Obesity: Body Mass Index (BMI) of 30 or higher.\ue2\u20ac\ua2 Body Mass Index (BMI): A measure of an adult\ue2\u20ac\u2122s weight in relation to his or her height, calculated by using the adult\ue2\u20ac\u2122s weight in ...

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Early causes of child obesity and implications for prevention

open access: yes, 2007
Child obesity is becoming a serious public health concern, and major research effort is being devoted both to understand its aetiology and to improve the effectiveness of prevention strategies.
Cole, T.J.
core  

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