Results 121 to 130 of about 2,083,740 (298)

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

A Synthesis of the Literature on the Relationship Between Food Access and Overweight and Obesity in African American Adolescents [PDF]

open access: yes, 2013
Food access shapes a community’s nutritional environment and impacts the health and physical well-being of its residents. When a community does not have adequate access to outlets that offer healthy options, it is difficult to maintain a healthy diet ...
Smalls, Marquita Noelle Bullock
core  

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

open access: yesAdvanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen   +16 more
wiley   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

open access: yesAdvanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee   +21 more
wiley   +1 more source

Metabolic sexual dimorphism in hypothalamic Fezf1 neuron-specific BDNF knockout

open access: yesBiology of Sex Differences
Background Brain-derived neurotrophic factor (BDNF) is highly expressed in the hypothalamus where it exerts regulatory functions over neurogenesis, reproduction, energy balance, and metabolism.
Dayana Cabral-da-Silva   +7 more
doaj   +1 more source

Current and Future Medical Costs of Childhood Obesity in Alaska [PDF]

open access: yes, 2014
This study examines the medical costs of childhood obesity in Alaska, today and in the future. We estimate that 15.2% of those ages 2 to 19 in Alaska are obese.
Guettabi, Mouhcine
core  

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

open access: yesAdvanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi   +12 more
wiley   +1 more source

Genotype subtyping approach to identify unnoticed variants in diseases from GWAS data

open access: yesBioData Mining
Genome-wide association studies (GWAS) are vital for investigating single-nucleotide polymorphisms (SNPs) in diseases. Comparisons of detected SNPs for the same disease between populations often reveal gaps, which are attributed to factors such as ...
Debora Garza-Hernandez   +2 more
doaj   +1 more source

Bariatric Surgery as a Treatment to Obesity [PDF]

open access: yes, 2019
This paper focuses on the efficiency and effectiveness that bariatric surgery provides as a treatment for the obesity epidemic that is ever-growing in our country. By taking into account scientific, ethnographical, scholarly, statistic-based, and various
Dunn, Morgan D
core   +1 more source

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

open access: yesAdvanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang   +9 more
wiley   +1 more source

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