Results 171 to 180 of about 2,007,139 (344)

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Association of dietary inflammatory index and Chinese healthy eating index with abdominal obesity in kidney transplant recipients. [PDF]

Asia Pac J Clin Nutr
Li Y, Zou Z, Huang H, Pan X, Liu Y, Tan R, Zhang C, Liu D, Xu S, Li Q.   +9 more
europepmc   +1 more source

Incidence of obesity and its predictors in children and adolescents in 10 years of follow up: Tehran lipid and glucose study (TLGS) [PDF]

, 2018
Maryam Barzin, Shayan Aryannezhad, Sara Serahati, Akram Beikyazdi, Fereidoun Azizi, Majid Valizadeh, Maryam Ziadlou, Farhad Hosseinpanah   +7 more
openalex   +1 more source

Protocol for the Rhode Island CORD 3.0 Study: Adapting, Testing, and Packaging the JOIN for ME Family-Based Childhood Obesity Program in Low-Income Communities

, 2021
Elissa Jelalian, E. Whitney Evans, Katherine E. Darling, Ronald Seifer, Patrick M. Vivier, Jeanne P. Goldberg, Catherine Wright, Lindsay A. Tanskey, Jennifer Warnick, Jacqueline F. Hayes, Donald S. Shepard, Hannah M. Tuttle, A. Rani Elwy   +12 more
openalex   +2 more sources

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Pharmacologic treatment of obesity in adults: Standards of care in overweight and obesity. [PDF]

BMJ Open Diabetes Res Care
American Diabetes Association Professional Practice Committee for Obesity.
europepmc   +1 more source

Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002.

Journal of the American Medical Association (JAMA), 2004
Allison A. Hedley, Cynthia L Ogden, C. Johnson, M. Carroll, L. Curtin, K. Flegal   +5 more
semanticscholar   +1 more source

EFFECT DIFFERENCES OF 30-MINUTES VERSUS 60-MINUTES TELE-EXERCISE ON FITNESS LEVEL OF OBESE EMPLOYEES

, 2022
Mury Kuswari, Rimbawan Rimbawan, Hardinsyah Hardinsyah, Mira Dewi, Nazhif Gifari   +4 more
openalex   +2 more sources

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source