Results 21 to 30 of about 1,339,496 (303)

Glycemic effects of quinine infusion in healthy volunteers

BMC Research Notes, 2017
Background We aimed to quantify the glycemic effects of quinine in healthy individuals. Methods We evaluated the glycemic profile in response to 4 h infusion of 500 ml of 0.9% saline versus 5% glucose solution with and without quinine at therapeutic dose
Audrey Carine Njomatchoua, Aurel Tiakouang Tankeu, Eugene Sobngwi, Jean-Claude Mbanya   +3 more
doaj   +1 more source

Criteria for EASO-collaborating centres for obesity management

, 2011
Obesity is recognised as a global epidemic and the most prevalent metabolic disease world-wide. Specialised obesity services, however, are not widely available in Europe, and obesity care can vary enormously across European regions.
Hermann Toplak, Tsigos, C., Volkan Yumuk, Yves Schutz, Yumuk, V., Schutz, Yves, Roman, Gabriela, Tsigos, Constantine, Dragan Micic, Maximo Maislos, Basdevant, A., Yumuk, Volkan, Nick Finer, Constantine Tsigos, Mathus-Vliegen, E., Schutz, Y., Barbara Zahorska-Markiewicz, Basdevant, Arnaud, Finer, N., Yumuk, Volkan Demirhan, Hainer, V., Finer, Nick, Roman, G., Arnaud Basdevant, Maislos, M., Micic, Dragan, Toplak, Hermann, Micic, D., Toplak, H., Gabriela Roman, Zahorska-Markiewicz, B., Mathus-Vliegen, Elisabeth, Zahorska-Markiewicz, Barbara, Elisabeth Mathus-Vliegen, Vojtech Hainer, Maislos, Maximo, Hainer, Vojtech   +36 more
core   +1 more source

An Under-the-Table Leg-Movement Apparatus and Changes in Energy Expenditure

Frontiers in Physiology, 2017
Introduction: Deskwork contributes substantially to sedentariness. Here, we evaluated an under-the-table apparatus that was designed to promote leg movement (fidgeting) while seated.
Gabriel A. Koepp, Graham Moore, James A. Levine, James A. Levine   +3 more
doaj   +1 more source

Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance

Nature Communications, 2020
Serotonin inhibits adipose tissue thermogenesis. Here the authors show that obese mice housed in thermoneutrality have increased mast cell serotonin synthesis, and that inhibiting this pathway through deletion of mast cell Tph1 increases white adipose ...
Julian M. Yabut, Eric M. Desjardins, Eric J. Chan, Emily A. Day, Julie M. Leroux, Bo Wang, Elizabeth D. Crane, Wesley Wong, Katherine M. Morrison, Justin D. Crane, Waliul I. Khan, Gregory R. Steinberg   +11 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The ‘Goldilocks Zone’ from a redox perspective - Adaptive versus deleterious responses to oxidative stress in striated muscle

Frontiers in Physiology, 2014
Consequences of oxidative stress may be beneficial or detrimental in physiological systems. An organ system’s position on the ‘hormetic curve’ is governed by the source and temporality of reactive oxygen species (ROS) production, proximity of ROS to ...
Rick J Alleman, Rick J Alleman, Lalage A Katunga, Lalage A Katunga, Margaret-Ann M Nelson, Margaret-Ann M Nelson, David A. Brown, David A. Brown, Ethan J Anderson, Ethan J Anderson   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Impact of obesity on the metabolic control of type 2 diabetes: Results of the Turkish nationwide survey of glycemic and other metabolic parameters of patients with diabetes mellitus (TEMD obesity study)

, 2019
Bu çalışmada sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.Background: Obesity is the main obstacle for metabolic control in patients with type 2 diabetes. Turkey has the highest prevalence of obesity and type 2 diabetes in Europe.
TEMD Obesity Study Group
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Tailoring limb length based on total small bowel length in one anastomosis gastric bypass surgery (TAILOR study): study protocol for a randomized controlled trial

Trials, 2022
Background The one anastomosis gastric bypass (OAGB) is being performed by an increasing number of bariatric centers over the world. However, the optimal length of the biliopancreatic (BP) limb remains a topic of discussion. Retrospective studies suggest
Nienke Slagter, Loek J. M. de Heide, Ewoud H. Jutte, Mirjam A. Kaijser, Stefan L. Damen, André P. van Beek, Marloes Emous   +6 more
doaj   +1 more source