Results 71 to 80 of about 3,410,787 (351)

The Complex Quest of Preventing Obesity in Early Childhood: Describing Challenges and Solutions Through Collaboration and Innovation

Frontiers in Endocrinology, 2022
Childhood obesity remains a major public health issue and priority area for action. Promisingly, obesity prevention interventions in the first 2000 days of life have shown modest effectiveness in improving health behaviours and healthy weight status in ...
Anna Lene Seidler, Anna Lene Seidler, Brittany J. Johnson, Brittany J. Johnson, Brittany J. Johnson, Rebecca K. Golley, Rebecca K. Golley, Rebecca K. Golley, Kylie E. Hunter, Kylie E. Hunter   +9 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Effect of apolipoprotein A-V on plasma triglyceride, lipoprotein size, and composition in genetically engineered mice

Journal of Lipid Research, 2008
Transgenic (Tg) mice that overexpress the human apolipoprotein A-V gene (APOA5) yet lack an endogenous mouse apoa5 gene (APOA5 Tg mice) were generated.
Lisa Nelbach, Xiao Shu, Robert J. Konrad, Robert O. Ryan, Trudy M. Forte   +4 more
doaj   +1 more source

What Does America Think About Childhood Obesity? [PDF]

, 2006
Presents findings from a survey of 1,108 adults that examines current attitudes about childhood obesity and measures support for various childhood obesity prevention ...

core  

Feasibility of Implementing Community Partnerships to Provide Diabetes Prevention Services to Youth [PDF]

, 2019
Type 2 diabetes (T2D) in youth has increased as a result of the obesity epidemic. Diabetes prevention programming is needed for youth, at risk for T2D, and their families.
Haberlin, Kathryn M., Hannon, Tamara S., Pike, Julie M., Yazel-Smith, Lisa   +3 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Protocol for the development of Core Outcome Sets for Early intervention trials to Prevent Obesity in CHildren (COS-EPOCH)

BMJ Open, 2021
Introduction Childhood overweight and obesity is prevalent in the first 5 years of life, and can result in significant health and economic consequences over the lifetime.
Marj Moodie, Marufa Sultana, Karen Matvienko-Sikar, Anna Lene Seidler, Kylie D Hesketh, Rachael Taylor, Kylie Elizabeth Hunter, Vicki Brown, Dorota Zarnowiecki, Rebecca Byrne, Huong Ngoc Quynh Tran, Rebecca Golley   +11 more
doaj   +1 more source

Understanding a successful obesity prevention initiative in children under 5 from a systems perspective

PLoS ONE, 2018
Introduction/Background Systems thinking represents an innovative and logical approach to understanding complexity in community-based obesity prevention interventions.
Brynle Owen, A. Brown, Jill A. Kuhlberg, L. Millar, M. Nichols, C. Economos, S. Allender   +6 more
semanticscholar   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Pharmacokinetic Simulation and Area under the Curve Estimation of Drugs Subject to Enterohepatic Circulation

Pharmaceutics
Enterohepatic circulation (EHC) is a complex process where drugs undergo secretion and reabsorption from the intestinal lumen multiple times, resulting in pharmacokinetic profiles with multiple peaks.
Melchor Alpízar, José de Jesús Reséndiz, Elisa García Martínez, Sanyog Dwivedi, Miguel Alejandro Trejo   +4 more
doaj   +1 more source