Results 11 to 20 of about 26,041 (228)

An integrated socio-cyber-physical system framework to assess responsible digitalisation in agriculture: A first application with Living Labs in Europe [PDF]

, 2022
Metta, M., Ciliberti, S., Obi, C., Bartolini, F., Klerkx, L., & Brunori, G. (2022). An integrated socio-cyber-physical system framework to assess responsible digitalisation in agriculture: A first application with Living Labs in Europe.
Metta, M, Bartolini, F., Ciliberti, S, Ciliberti, S., Fabio Bartolini, Gianluca Brunori, Laurens Klerkx, Brunori, G., Stefano Ciliberti, Matteo Metta, Bartolini, F, Obi, C., Brunori, G, Klerkx, L, Chinedu Obi, Obi, C, Klerkx L., Metta M., Ciliberti S., Brunori G., Obi C., Bartolini F.   +21 more
core   +1 more source

Study on the hepatitis B virus infection in blood donors reactive to jointed NAT but non-reactive to primary discriminatory test

Zhongguo shuxue zazhi, 2022
Objective To analyze the status of HBV infection in blood donors reactive to jointed NAT but non-reactive to primary discriminatory tests (NRR), so as to provide suggestions and data support for subsequent studies on NRR samples.
Fengyuan LI, Tong PAN, Xia WANG, Fuhua ZHANG, Huafei GONG   +4 more
doaj   +1 more source

Epidemiology of occult hepatitis B and C in Africa: A systematic review and meta-analysis

Journal of Infection and Public Health, 2022
Background: Occult hepatitis B (OBI) and C (OCI) infections lead to hepatic crises including cases of liver cirrhosis and even hepatocellular carcinoma (HCC). OBI and OCI also pose a significant problem of their transmissibility.
Juliette Laure Ndzie Ondigui, Sebastien Kenmoe, Cyprien Kengne-Ndé, Jean Thierry Ebogo-Belobo, Guy Roussel Takuissu, Raoul Kenfack-Momo, Donatien Serge Mbaga, Serges Tchatchouang, Josiane Kenfack-Zanguim, Robertine Lontuo Fogang, Elisabeth Zeuko'o Menkem, Ginette Irma Kame-Ngasse, Jeannette Nina Magoudjou-Pekam, Arnol Bowo-Ngandji, Nadège Mafopa Goumkwa, Seraphine Nkie Esemu, Lucy Ndip, Sara Honorine Riwom Essama, Judith Torimiro   +18 more
doaj   +1 more source

The Ontology for Biomedical Investigations.

PLoS ONE, 2016
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted.
Anita Bandrowski, Ryan Brinkman, Mathias Brochhausen, Matthew H Brush, Bill Bug, Marcus C Chibucos, Kevin Clancy, Mélanie Courtot, Dirk Derom, Michel Dumontier, Liju Fan, Jennifer Fostel, Gilberto Fragoso, Frank Gibson, Alejandra Gonzalez-Beltran, Melissa A Haendel, Yongqun He, Mervi Heiskanen, Tina Hernandez-Boussard, Mark Jensen, Yu Lin, Allyson L Lister, Phillip Lord, James Malone, Elisabetta Manduchi, Monnie McGee, Norman Morrison, James A Overton, Helen Parkinson, Bjoern Peters, Philippe Rocca-Serra, Alan Ruttenberg, Susanna-Assunta Sansone, Richard H Scheuermann, Daniel Schober, Barry Smith, Larisa N Soldatova, Christian J Stoeckert, Chris F Taylor, Carlo Torniai, Jessica A Turner, Randi Vita, Patricia L Whetzel, Jie Zheng   +43 more
doaj   +1 more source

Occult Hepatitis B and Other Unexplored Risk Factors for Hepatocellular Carcinoma in Latin America

Annals of Hepatology, 2018
Occult hepatitis B infection (OBI) is the presence of hepatitis B virus (HBV) DNA in the liver and/or serum (< 200 IU/mL) in HBsAg-negative patients with or without serologic markers of previous viral exposure.
Sonia Roman
doaj   +1 more source

Identification and characterization of interferon signaling-related microRNAs in occult hepatitis B virus infection

Clinical Epigenetics, 2017
Background Occult hepatitis B virus infection (OBI) is an important risk factor of liver cirrhosis and hepatocellular carcinoma. Type 1 interferon (IFN) signaling-related miRNAs were significantly associated with hepatitis B virus (HBV) infection ...
Yiying Wang, Peifu Zhu, Jing Qiu, Jie Wang, Huijuan Zhu, Yinwei Zhu, Lige Zhang, Jie Zhu, Xingxiang Liu, Chen Dong   +9 more
doaj   +1 more source

Role of S protein transmembrane domain mutations in the development of occult hepatitis B virus infection

Emerging Microbes and Infections, 2022
Occult HBV infection (OBI) is a special infection status during Hepatitis B virus (HBV) infection. The underlying mechanism of its occurrence remains unclear.
Xinyi Jiang, Le Chang, Ying Yan, Huimin Ji, Huizhen Sun, Yingzi Xiao, Shi Song, Kaihao Feng, Abudulimutailipu Nuermaimaiti, Lunan Wang   +9 more
doaj   +1 more source

Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia

Nature Communications, 2023
Data on long-term outcomes and biological drivers associated with depth of remission after BCL2 inhibition by venetoclax in the treatment of chronic lymphocytic leukemia (CLL) are limited.
Othman Al-Sawaf, Can Zhang, Hyun Yong Jin, Sandra Robrecht, Yoonha Choi, Sandhya Balasubramanian, Alex Kotak, Yi Meng Chang, Anna Maria Fink, Eugen Tausch, Christof Schneider, Matthias Ritgen, Karl-Anton Kreuzer, Brenda Chyla, Joseph N. Paulson, Christian P. Pallasch, Lukas P. Frenzel, Martin Peifer, Barbara Eichhorst, Stephan Stilgenbauer, Yanwen Jiang, Michael Hallek, Kirsten Fischer   +22 more
doaj   +1 more source

Development and validation of pharmacokinetic assays for OBI-992, a TROP2-directed ADC: Application to human pharmacokinetic study

Talanta Open
OBI-992 is a novel TROP2-targeted antibody–drug conjugate (ADC) composed of an anti-TROP2 monoclonal antibody conjugated to exatecan, a potent topoisomerase I (TOP1) inhibitor, via an enzyme-cleavable hydrophilic linker. OBI-992 is being assessed for its
Shih-Ni Wen, Chi-Sheng Shia, Yu-Hsuan Tsao, Hui-Wen Chang, Xiaonan Liu, Guannan Song, Fei Meng, Tao Xu, Jyy-Shiuan Tu, Ren-Yu Hsu, Ya-Chi Chen   +10 more
doaj   +1 more source

A computational approach to identify point mutations associated with occult hepatitis B: significant mutations affect coding regions but not regulative elements of HBV

Virology Journal, 2011
Background Occult Hepatitis B Infection (OBI) is characterized by absence of serum HBsAg and persistence of HBV-DNA in liver tissue, with low to undetectable serum HBV-DNA. The mechanisms underlying OBI remain to be clarified.
Presti Alessandra, Tritarelli Elena, Villano Umbertina, Amadori Alessandra, Marcantonio Cinzia, Prosperi Mattia, Bruni Roberto, Ciccozzi Massimo, Ciccaglione Anna R   +8 more
doaj   +1 more source