Results 41 to 50 of about 3,225,497 (280)
Advanced Science, EarlyView.Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang +6 more
wiley +1 more source
Current Swedish Archaeology, 2014 Most entities studied by archaeologists share the same basic necessary conditions. They are limited spatiotemporal units which are continuous within a human frame of sensorial reference.
Johan Normark
doaj +1 more source
Advanced Science, EarlyView.In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han +10 more
wiley +1 more source
Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
Advanced Science, EarlyView.The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source
American Objects vs. Austrian Objects
, 2010 Presented at the first Object-Oriented Ontology Symposium, April 23, 2010, Georgia Tech Hotel, Atlanta, GeorgiaGraham Harman is Associate Vice Provost for Research and Associate Professor of Philosophy at the American University in Cairo.
Crawford, Hugh +5 more
core +1 more source
THE ANALYSES OF BUSINESS PROCESS CONCEPTUAL MODEL BASED ON BUNGE-WAND-WEBER ONTOLOGY
Статистика и экономика, 2016 This article discusses the Bunge-Wand-Weber representation ontology that is widely used for business process modeling and in object oriented IT development.
Igor G. Fedorov
doaj +1 more source
Bio-Ontology Generation Using Object-Oriented Ontology Manager [PDF]
The KIPS Transactions:PartB, 2004 This paper presents an approach to the development of bio-ontology using the Object-oriented Ontology Manager(OOM). OOM views a term of an ontology as an object which can be an instance or a concept. OOM facilitates the semi-automatic construction of ontologies by an intuitive interface and by inferencing with links among complicated and informative ...
openaire +1 more source
A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation
Advanced Science, EarlyView.A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang +5 more
wiley +1 more source
Object-Oriented Baudrillard? Withdrawal and Symbolic Exchange
Open Philosophy, 2019 By comparing Object-Oriented Ontology (OOO) and Baudrillard through the lens of a study of the notion of withdrawal in Heidegger’s tool analysis and “The Question Concerning Technology”, this article explores the extent to which an Object-Oriented ...
King Matthew James
doaj +1 more source
Advanced Science, EarlyView.A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie +7 more
wiley +1 more source