Results 81 to 90 of about 292,707 (348)
Advanced Science, EarlyView.Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun +14 more
wiley +1 more source
A semantic web services-based infrastructure for context-adaptive process support [PDF]
, 2007 Current technologies aimed at supporting processes whether it is a business or learning process - primarily follow a metadata- and data-centric paradigm.
Dietze, Stefan +2 more
core +1 more source
Advanced Science, EarlyView.This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley +1 more source
Flexible coordination techniques for dynamic cloud service collaboration [PDF]
, 2012 The provision of individual, but also composed services is central in cloud service provisioning. We describe a framework for the coordination of cloud services, based on a tuple‐space architecture which uses an ontology to describe the services. Current
Creaner, Gary, Pahl, Claus
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Advanced Science, EarlyView.This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu +6 more
wiley +1 more source
Cross-species Harmony: Horses and Humans Co-Creating and Immersed in Shared Worlds
European Journal of American StudiesDespite efforts to democratize horse/human relations, conceptions of harmony between horses and humans continue to privilege the human’s will, even in more progressive models of horsemanship.
Sarah Allen
doaj +1 more source
Вісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії, 2018 The article investigates place of an object in the field of speculative realism in general and objectoriented ontology in particular. It describes object’s special and ambiguous position given to it by OOO as opposed to “correlational” approach.
Vitalii O. Starovoit
doaj +1 more source
Advanced Science, EarlyView.The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan +13 more
wiley +1 more source
GOMS: Large-scale ontology management system using graph databases
ETRI Journal, 2022 Large-scale ontology management is one of the main issues when using ontology data practically. Although many approaches have been proposed in relational database management systems (RDBMSs) or object-oriented DBMSs (OODBMSs) to develop large-scale ...
Chun-Hee Lee, Dong-oh Kang
doaj +1 more source
Ontology: Towards a new synthesis [PDF]
, 1998 This introduction to the second international conference on Formal Ontology and Information Systems presents a brief history of ontology as a discipline spanning the boundaries of philosophy and information science.
Smith, Barry, Welty, Chris
core