Results 101 to 110 of about 3,017,861 (368)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Attachment and separation-individuation process among young adults as volunteers in the field of psychosocial help [PDF]

open access: yesPsihološka Obzorja, 2008
Distinctions among different attachment styles often appear to be unclear. These distinction inadequacies also result from superficial knowledge of psychodynamic factors of the attachment system, which the concept of internal working models often ...
Leonida Kobal Možina
doaj  

Study of a quasi-microscope design for planetary landers [PDF]

open access: yes
The Viking Lander fascimile camera, in its present form, provides for a minimum object distance of 1.9 meters, at which distance its resolution of 0.0007 radian provides an object resolution of 1.33 millimeters.
Brown, E. B., Giat, O.
core   +1 more source

Affective Sustainability. Is this what timelessness really means? [PDF]

open access: yes, 2009
Sustainability is always about regard to the environment: an intelligent use of resources and not returning to nature what it cannot degrade without long-term damage.
Borjesson, Kristina
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Women’s Attachment as a Predictor of Pain During Labour and Post-Delivery: a Prospective Observational Study

open access: yesActa Médica Portuguesa, 2014
Introduction: Labour is considered to be one of the most painful and significant experiences in a woman’s life. The aim of this study was to examine whether women’s attachment style is a predictor of the pain experienced throughout labour and post ...
José Manuel Costa Martins   +7 more
doaj   +1 more source

Apartheid's lost attachments (2): melancholic loss and symbolic identification [PDF]

open access: yes
This paper, the second of two focussed on the libidinal attachments of white children to black domestic workers in narratives contributed to the Apartheid Archive Project (AAP), considers the applicability of the concept of social melancholia in the case
Hook, Derek
core  

Attachment

open access: yesRekindling Desire, 2018
P erhaps it is the security that modern urban societies have developed for their intellectuals that has given rise to their habits of detachment: critically distanced analysis, ironic commentary, skepticism that can veer quickly to cynicism.
Barry McCarthy, E. Mccarthy
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Attachment is a dynamic system [PDF]

open access: yesPsihološka Obzorja, 2003
On the basis of the study of recent scientific literature about the development of attachment, the author answers the following questions: which are the postulates the theory of attachment has about the stability of the patterns of attachment, which ...
Zlatka Cugmas
doaj  

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