Results 81 to 90 of about 2,375,655 (290)

Working Smarter Not Harder: Oxytocin Increases Domestic Dogs’ (Canis familiaris) Accuracy, but Not Attempts, on an Object Choice Task

Frontiers in Psychology, 2019
The neuropeptide oxytocin (OT) has been shown to enhance dogs’ ability to perform an object choice task (OCT) involving the use of human pointing cues, when delivered intranasally.
Jessica Lee Oliva, Manuel Mengoli, Manuel Mengoli, Tiago Mendonça, Tiago Mendonça, Alessandro Cozzi, Patrick Pageat, Patrick Pageat, Camille Chabaud, Eva Teruel, Céline Lafont-Lecuelle, Cécile Bienboire-Frosini   +11 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Women’s Attachment as a Predictor of Pain During Labour and Post-Delivery: a Prospective Observational Study

Acta Médica Portuguesa, 2014
Introduction: Labour is considered to be one of the most painful and significant experiences in a woman’s life. The aim of this study was to examine whether women’s attachment style is a predictor of the pain experienced throughout labour and post ...
José Manuel Costa Martins, Carlos Fernandes da Silva, Marco Pereira, Henriqueta Martins, Célia Oliveira, Alexandra Puga, Rui Coelho, Jorge Tavares   +7 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Digitally Mediated Attachment Regulation: A Conceptual Clinical Model

Psychotherapy and Counselling Journal of Australia
Minimal digital cues–read receipts, online status indicators, and response latency–can acquire disproportionate emotional significance for individuals with high attachment vulnerability.
Tobey Gross
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Attachment and Object-Relations Theory

, 1996
This thesis investigates associations between Attachment Theory and Psychoanalytic Object-Relations Theory. Major psychoanalytic theories are reviewed (Feud, Klein, Fairbairn, Winnicott, Kohut, Kernberg). Theoretical links are made with Attachment Theory
China, Jacques Lefebvre
core  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Attachment for Object Finders.

, 1915
Patent for a "new and useful attachment for the object finder of a camera" (lines 9-10) with adjustable configuration, including ...
Lawson, Harry C.
core