Results 71 to 80 of about 41,772 (257)

For the love of things: an interdisciplinary exploration of object attachment [PDF]

open access: yes, 2022
From teddy bears to wedding rings, all humans are capable of developing close attachments to certain objects. Yet, despite these attachments being ubiquitous, they have received almost no attention from archaeology, and misconceptions abound. This thesis
Bell, Taryn
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Adolescent Twins’ Mental Representations of Self and Other in Relation with Zygosity, Attachment Patterns and Psychological Disturbances

open access: yes, 2015
Introduction: Based on a theoretical integration of cognitive development psychology, psychoanalytic theory and attachment theory, Blatt and his colleagues formulated a systematic psychodynamic model of mental representation of self and other emphasizing
Zhou, Y
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

INISIASI MENYUSU DINI DAN BOUNDING ATTACHMENT DALAM PENINGKATAN KESEHATAN SECARA FISIK DAN PSIKIS

open access: yesJUMANTIK (Jurnal Ilmiah Penelitian Kesehatan), 2017
Early breastfeeding initiation is a breastfeeding process that begins immediately after the baby is born by allowing the baby skin to skin contact for at least the first hour after birth or until the initial feeding process ends.
Fauziah Nasution, M.Psi
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Examining the importance of the family on pre-school attachment and children's social development

open access: yes, 2012
Contemporary accounts of attachment theory are usually provided in terms of the mother-child dyad, isolated from the family. This focus has served to ostracise the caregiving context, once viewed as central to understanding child attachment quality ...
Kennedy, M
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Early Attachment Disruption, Inflammation, and Vulnerability for Depression in Rodent and Primate Models

open access: yesFrontiers in Behavioral Neuroscience, 2019
Early experiments in nonhuman primates established the relation between disruption of filial attachment and depressive-like outcomes. Subsequent studies in rats and mice have been instrumental in linking depressive-like outcomes to disturbances in ...
Michael B. Hennessy   +4 more
doaj   +1 more source

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