Results 71 to 80 of about 2,440,837 (298)

Examining the importance of the family on pre-school attachment and children's social development [PDF]

open access: yes, 2012
Contemporary accounts of attachment theory are usually provided in terms of the mother-child dyad, isolated from the family. This focus has served to ostracise the caregiving context, once viewed as central to understanding child attachment quality ...
Kennedy, M
core  

Women’s Attachment as a Predictor of Pain During Labour and Post-Delivery: a Prospective Observational Study

open access: yesActa Médica Portuguesa, 2014
Introduction: Labour is considered to be one of the most painful and significant experiences in a woman’s life. The aim of this study was to examine whether women’s attachment style is a predictor of the pain experienced throughout labour and post ...
José Manuel Costa Martins   +7 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Romantic attachment and commitment: a mediation model

open access: yes, 2017
As defined by Bowlby (1969, 1982), attachment system is directed to maintain closeness to a significant other who is able to give support and protection in dangerous situations.
BRUNETTO, MARTINA   +3 more
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Development of attachment and the role of father-mother-child relationship in families with a preterm baby: a preliminary report.

open access: yes, 2008
The aim of the research unit is to study the development of attachment, the psychological difficulties and the role of Father-Mother-Child relationship in the family with preterm birth child.
E. Facondini   +3 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

INISIASI MENYUSU DINI DAN BOUNDING ATTACHMENT DALAM PENINGKATAN KESEHATAN SECARA FISIK DAN PSIKIS

open access: yesJUMANTIK (Jurnal Ilmiah Penelitian Kesehatan), 2017
Early breastfeeding initiation is a breastfeeding process that begins immediately after the baby is born by allowing the baby skin to skin contact for at least the first hour after birth or until the initial feeding process ends.
Fauziah Nasution, M.Psi
doaj   +1 more source

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