Results 91 to 100 of about 4,941,756 (276)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
In this work we present the result of an analysis of a mother-language class delivered to students of the 6th grade of fundamental school in a public school at the periphery of the city of Campinas/ SP.
Milene Bazarim, Inês Signorini
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Binary histogram based split/merge object detection using FPGAs [PDF]
Tracking of objects using colour histograms has proven successful in various visual surveillance systems. Such systems rely heavily on similarity matrices to compare the appearance of targets in successive frames.
Hunter, A +7 more
core +1 more source
A RELATION BETWEEN WEB PAGES [PDF]
In this paper we define a relation on the set of web pages from a web application. With the help of this relation, we obtain a partition of this set into subsets.
DORU ANASTASIU POPESCU
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Object Oriented Computing [PDF]
In this contribution, the basic overview of the Object Oriented Programming and its usage in computation is given. Concepts of class, encapsulation, inheritance, and polymorphism are introduced. Some additional concepts like interface and Design Patterns
Virius, Miroslav
core

