Results 121 to 130 of about 296,550 (316)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Real-time multiple object tracking using virtual shells [PDF]

, 2012
This paper presents a new multiple object tracking framework where arbitrarily shaped complex objects having severe occlusions are successfully tracked in real-time using stationary cameras.
Erdoğan, Hakan, Kekeç, İbrahim Taygun, Ünel, Mustafa   +2 more
core  

Insignificant shadow detection for video segmentation

, 2005
To prevent moving cast shadows from being misunderstood as part of moving objects in change detection based video segmentation, this paper proposes a novel approach to the cast shadow detection based on the edge and region information in multiple frames.
Tang, X., Jianzhuang Liu, Li, Xuelong, Liu, Z., Xu, Dong, Liu, Jianzhuang, Liu, Zhengkai, Xiaoou Tang, Xu, D., Zhengkai Liu, Dong Xu, Liu, J., Tang, Xiaoou, Senior Member, Xuelong Li   +14 more
core   +1 more source

Exploiting contextual data for event retrieval in surveillance video [PDF]

, 2009
Contextual information is vital for the robust extraction of semantic information in automated surveillance systems. We have developed a scene independent framework for the detection of events in which we provide 2D and 3D contextual data for the scene ...
Ó Conaire, Ciarán, O'Connor, Noel E., Ciarán Ó Conaire, Kelly, Philip, Philip Kelly, Noel E. O'Connor   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subspace discovery for video anomaly detection

, 2010
PhDIn automated video surveillance anomaly detection is a challenging task. We address this task as a novelty detection problem where pattern description is limited and labelling information is available only for a small sample of normal instances.
Tziakos, Ioannis
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Source-Free Object Detection With Detection Transformer

IEEE Transactions on Image Processing
IEEE Transactions on Image ...
Huizai Yao, Sicheng Zhao, Shuo Lu, Hui Chen 0013, Yangyang Li, Guoping Liu, Tengfei Xing, Chenggang Yan 0001, Jianhua Tao 0001, Guiguang Ding   +9 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source