Results 51 to 60 of about 3,549,980 (276)

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

Advanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang, Huadong Xing, Antonella Di Pizio, Qinfei Ke, Xingran Kou, Dachuan Zhang   +5 more
wiley   +1 more source

Cross-species Harmony: Horses and Humans Co-Creating and Immersed in Shared Worlds

European Journal of American Studies
Despite efforts to democratize horse/human relations, conceptions of harmony between horses and humans continue to privilege the human’s will, even in more progressive models of horsemanship.
Sarah Allen
doaj   +1 more source

"TRANSNOUMENALISM" AND OBJECT-ORIENTED ONTOLOGY: REAL, IMAGINARY AND CONSTITUTION OF OBJECTIVITY WITHIN THE FRAMEWORK OF SPECULATIVE REALISM

Вісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії, 2018
The article investigates place of an object in the field of speculative realism in general and objectoriented ontology in particular. It describes object’s special and ambiguous position given to it by OOO as opposed to “correlational” approach.
Vitalii O. Starovoit
doaj   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

GOMS: Large-scale ontology management system using graph databases

ETRI Journal, 2022
Large-scale ontology management is one of the main issues when using ontology data practically. Although many approaches have been proposed in relational database management systems (RDBMSs) or object-oriented DBMSs (OODBMSs) to develop large-scale ...
Chun-Hee Lee, Dong-oh Kang
doaj   +1 more source

Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli

Advanced Science, EarlyView.
Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma, Yuxin Zhang, Lujia Sun, Hong Jiang, Fan Li, Wenming Liu, Shenao Zhou, Mengting Wang, Weijian Huang, Xu Zhou, Caiyang Chen, Qiuqiu Zhang, Xiaoyan Jin, Feihan Yan, Hongping Wu, Yonghong Yin, Xinling Wang, Hexin Yan, Weifeng Yu   +18 more
wiley   +1 more source

Top-level categories of constitutively organized material entities--suggestions for a formal top-level ontology.

PLoS ONE, 2011
BackgroundApplication oriented ontologies are important for reliably communicating and managing data in databases. Unfortunately, they often differ in the definitions they use and thus do not live up to their potential.
Lars Vogt, Peter Grobe, Björn Quast, Thomas Bartolomaeus   +3 more
doaj   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Contesti in volo

Ardeth, 2018
Traditional design tools and procedures are not always appropriate to tackle the continuous movement of buildings and contexts. Starting from such apt consideration by Latour and Yaneva, this essay reflects on the issues that the introduction of movement
Pepe Barbieri
doaj