Results 71 to 80 of about 3,549,980 (276)

Rethinking Organismic Unity: Object-Oriented Ontology and the Human Microbiome

Open Philosophy
In recent years, a vast array of thinkers have been invested in challenging the long-standing binary division between the human and nonhuman. The notion of the human microbiome especially attests to the truth of such a complication, since current ...
Young Niki, Lanfranco Sandro
doaj   +1 more source

The Knowable and the Ineffable: an object-oriented reading of Enric Miralles’ design approach

Cuadernos de Proyectos Arquitectónicos, 2019
Abtract This paper links the current philosophical stance of Object-oriented Ontology (OOO) to Enric Miralles’ design approach in the late 20th century.
Gonzalo Vaíllo
doaj   +1 more source

New trend in object oriented image analysis -Ontology

, 2020
Spatial data is used for many purposes in city administration such as solving problems of living areas, establishing healthy and sustainable cities and establishing the infrastructure of smart cities. For this reason, collection, processing, evaluation and transformation of spatial data are important for quick and accurate decisions of city ...
Sener, Zeynep, Uzar, Melis
openaire   +2 more sources

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Chrysanthemum Morifolium–Derived Nanovesicles Reduce Lactate‐Associated Histone Lactylation and Modulate Microglia‐Mediated Neuroinflammation in Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
When used to treat sepsis‐associated encephalopathy, Chrysanthemum morifolium–derived nanovesicles can inhibit the H3K18la/NF‐κB axis to regulate microglia‐mediated neuroinflammation. ABSTRACT Sepsis‐associated encephalopathy (SAE)—a complication of the central nervous system in patients with sepsis—markedly diminishes cognitive functions and is linked
Kaiqiang Li, Xuling Luo, Xiaoting Zhang, Chengwen He, Wei Xu, Aibo Xu, Shushan Hua, Liping Wang, Liang Ma, Ke Hao, Youmin Ying, Zhen Wang   +11 more
wiley   +1 more source

“Get the Tone Right”: Reading with the Realism of Object-Oriented Ontology

Open Philosophy, 2018
This paper investigates the consequences of taking seriously the metaphysics of Object-Oriented Ontology (OOO), as defined by Graham Harman, in the field of literature. Acutely focusing on just one possible mobilisation and application of the theory, the
Wei-Hao Chin Gabriel Patrick
doaj   +1 more source

Stage‐Adaptive Bilayer Hydrogel Coordinates Photodynamic Antibacterial Therapy with Engineered Extracellular Vesicle–Mediated Immunomodulation in Infected Diabetic Wounds

Advanced Science, EarlyView.
Early photodynamic infection control and subsequent immunoregulatory repair are spatially separated within a stage‐adaptive bilayer hydrogel. Chlorin e6 is incorporated into the wound‐contacting layer to provide light‐triggered bactericidal therapy, whereas the upper layer regulates excessive reactive oxygen species before releasing microRNA‐146a ...
Gaofei Zhang, Boheng Zhu, Shihao Deng, Pan Du, Jun Pu, Xin Wang, Shuqian Dou, Yifei Wang, Wenjun Liu   +8 more
wiley   +1 more source

Objects, Relations, Potential and Change

Open Philosophy, 2020
This article attempts to develop further the conception of dynamics in Object-Oriented Ontology (OOO): its model of how objects develop and change. Objects are affected by relations between them, and have the potential both to produce and undergo effects,
Nooteboom Bart
doaj   +1 more source

Development‐Informed Microsphere Assemblies Enable Spatiotemporally Programmed Bone–Vascular Organoid‐Like Constructs for Large Bone Defect Repair

Advanced Science, EarlyView.
Single‐cell‐guided prioritization of BMP4 and VEGFA is combined with temporally programmed BMSCs and a Matrigel‐free GelMA/PEO/bioactive‐glass assembled‐microsphere matrix to generate bone–vascular organoid‐like constructs. The platform coordinates osteogenic differentiation, endothelial activation, vascular‐like microchannel formation, and ...
Renhao Ni, Xinyi Shi, Tong Zhu, Guanrong Li, Lei Chang, Shengtao Li, Jingyi Chi, Chen Shi, Zeming Hu, Rong Xu, Yingchun Zhu, Yang Luo, Yichen Chen, Fan Yang, Yabin Zhu   +14 more
wiley   +1 more source

A formal model of the Semantic Web Service Ontology (WSMO) [PDF]

, 2012
Semantic Web Service, one of the most significant research areas within the Semantic Web vision, has attracted increasing attention from both the research community and industry.
Payne, T.R., Nick Gibbins, Wang, H.W., Redavid, D., Hai H. Wang, Wang, Hai, Gibbins, Nick, Payne, Terry, Terry R. Payne, Gibbins, N., Redavid, Domenico, Domenico Redavid, Redavid D., Gibbins N., Payne T. R., Wang H. H.   +15 more
core   +1 more source