Results 121 to 130 of about 326,825 (301)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Video Chat Application for Facebook [PDF]

open access: yes, 2011
This project is mainly written for the facebook users. In today’s world, there are many social networking sites available. Among those social networking web sites, facebook is widely used web site.
Chokshi, Shirali
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Focus structure and the referential status of indefinite quantificational expressions [PDF]

open access: yes, 2013
Many authors who subscribe to some version of generative syntax account for the two readings of [...] sentences [...] in terms of LF-ambiguity. There is assumed to be covert quantifier raising (QR), which results in two distinct possibilities for the ...
Breul, Carsten
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

When are adjectives raisers? Tough to get it

open access: yesBucharest Working Papers in Linguistics, 2007
This article deals with some unsolved problems raised by tough-adjectives in Romance languages. We present some new data from some Romance languages (Romanian, French, Italian) supporting a raising analysis, and we argue that in these languages, unlike ...
Ion Giurgea, Elena Soare
doaj  

Should the law allow sentiment to triumph over science? The retention of body parts [PDF]

open access: yes, 2002
The use of human body material including tissue and organs has been controversial for many centuries. Concerns arose in the eighteenth century about practices used to obtain corpses for dissection.
Thomas, C. M.
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Counting markedness : a corpus investigation on German free relative constructions [PDF]

open access: yes, 2004
This paper reports the results of a corpus investigation on case conflicts in German argument free relative constructions. We investigate how corpus frequencies reflect the relative markedness of free relative and correlative constructions, the relative ...
Vogel, Ralf, Zugck, Marco
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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