Caregiver distress explains links between objective and subjective socioeconomic status and adolescent internalizing and externalizing behaviors. [PDF]
Miller P +5 more
europepmc +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Can Mutual Fund Managers Pick Stocks? Evidence from the Trades Prior to Earnings Announcements [PDF]
We test whether fund managers have stock-picking skill by comparing their holdings and trades prior to earnings announcements with the returns realized at those events.
Jessica A. Wachter +3 more
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Long-term neurological consequences of hypertensive disorders of pregnancy: Implications for postpartum monitoring and intervention. [PDF]
Hagood M, Lucke-Wold B.
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The problems with design education in the UK
The objective of this paper is to explore the problems associated with design education in the UK. British Design has an enviable international reputation for excellence, however, has this reputation been gained at the expense of its student body? And is
Prior, Stephen D. +2 more
core
Serological Profiling and Neuro-Immune Resilience: The Dissociation Between Anti-SARS-CoV-2 Antibodies and Post-Viral Airway Hyperresponsiveness in Pediatric Asthma. [PDF]
Kunc P +4 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
An objective approach to prior mass functions for discrete parameter spaces.
We present a novel approach to constructing objective prior distributions for discrete parameter spaces. These types of parameter spaces are particularly problematic, as it appears that common objective procedures to design prior distributions are ...
Walker SG, Villa C
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