Results 121 to 130 of about 14,308,489 (319)
CURRENT SITUATION AND CONCEPTUAL PROBLEMS OF DEVELOPMENT AND OPPERATION OF THE INTEGRATED INFORMATION SYSTEMS OF ECONOMIC MANAGEMENT [PDF]
Economica, 2018 The management of economic system, as a unitary information and material nucleus, that acts automatically, in real-time, is analysed in the present work.
Tudor LEAHU +2 more
doaj
PERFORMANCE OBJECTIVES IN FOOD RETAILING [PDF]
Develops a system for management by objectives and applies the system to the retail food industry.Agribusiness,
Leed, Theodore W., Mead, Kenneth W.
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Leveling transparency via situated intermediary learning objectives (SILOs) [PDF]
, 2014 When designers set out to create a mathematics learning activity, they have a fair sense of its objectives: students will understand a concept and master relevant procedural skills.
Abrahamson, D +3 more
core
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Objetivos de organizações culturais sem fins lucrativos e suas fontes financiadoras
Cadernos EBAPE.BRA fim de compreender as mudanças no contexto das organizações culturais, apresenta-se uma reflexão sobre as transformações nos objetivos de dois grupos teatrais sem fins lucrativos de Florianópolis-SC e sobre a influência que os critérios requeridos ...
Samara Regina Bernardino Hoffmann +2 more
doaj +1 more source