Results 141 to 150 of about 2,920,140 (298)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Determination and Evaluation of UAV Safety Objectives
, 2006 The integration and acceptance of routine Unmanned Aerial Vehicle (UAV) operations within the civilian airspace system hinges on the ability of UAV developers, operators and regulators to prove that UAVs, at minimum, have an equivalent level of safety to
Walker, Rodney A., Clothier, Reece A.
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Using a modified DEA model to estimate the importance of objectives. An application to agricultural economics. [PDF]
This paper shows a connection between Data Envelopment Analysis (DEA) and the methodology proposed by Sumpsi et al. (1997) to estimate the weights of objectives for decision makers in a multiple attribute approach.
Laura Riesgo +2 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The Essence of Higher Education Instruction
The Journal of Studies in Language, Culture and SocietyTo respond to the dynamic global changes, the Algerian Higher Education has constantly brought reforms aiming at enhancing the learning outcomes and more importantly to define the optimal objectives necessary for students to enter the professional world.
Naziha Benosmane
doaj
How to Design and Implement a Structured Curriculum in Health Professions Education: A Nine-Step Framework Building on Kern's Approach. [PDF]
Clin TeachEscourrou É, Oustric S.
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Treeline Provides a Unified Strategy for Optimising Phylogenetic Trees Under Alternative Criteria. [PDF]
Mol Ecol ResourWright ES.
europepmc +1 more source
Managing Forests for Multiple Tradeoffs: Compromising on Timber, Carbon, and Biodiversity Objectives [PDF]
In this paper, we develop a multiple objective, decision-making model that focuses on forest policies that simultaneously achieve carbon uptake and maintenance of ecosystem diversity objectives.
Ilan Vertinsky +2 more
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