Results 221 to 230 of about 323,203 (269)
Some of the next articles are maybe not open access.
The Trials of the Gas Mask An Object of Fumbling
Diogenes, 1993It was during the Gulf War that I discovered the gas mask to be an object. As it became increasingly credible and imminent, the unfathomable menace was crucially rescaled to the toxic potency and dispersal pattern of law-abiding molecules. So it went with the gas mask: the Gulf War transformed it from a vaguely morbid mental image into a facial object ...
openaire +1 more source
Superchain procedures in clinical trials with multiple objectives
Statistics in Medicine, 2012This paper introduces a new class of multiple testing procedures for addressing multiplicity problems arising in clinical trials with multiple objectives grouped into families. The families may correspond to equally important sets of objectives (co‐primary endpoints) or ordered sets of objectives (primary and secondary endpoints).
Kordzakhia, George, Dmitrienko, Alex
openaire +2 more sources
The Competing Objectives of Randomized Trials
New England Journal of Medicine, 1980The intervention trial of greatest benefit to patients satisfies three objectives: validity (its results are true), generalizability (its results are widely applicable), and efficiency (the trial i...
openaire +1 more source
Objectivity and elites: A creation science trial
Critical Studies in Mass Communication, 1988The recent controversy over “scientific creationism” represents an intriguing case study of the interpenetration of the paradigm discourses of science, religion, politics, and law and public motive structures. Despite nearly unanimous judicical rejection, creationist claims for “balanced treatment” with evolution in the public schools have received an ...
Charles Alan Taylor +1 more
openaire +1 more source
Character Evidence and the Object of Trial
Columbia Law Review, 2001Evidence of an individual's character may not in general be offered to prove that she acted in conformity with that character on a particular occasion. Most analyses of this general rule?and its many exceptions?start from the premise that trial is at heart an exercise in finding facts.
openaire +1 more source
Ancient Philosophy, 2022
I analyse Theaet. 200e-201c. I hold that this passage provides specific insights into: first, the nature of sensible things and events; second, the nature of knowledge. I show that the text should be taken as an analogy, which means that Plato does not consider eye-witnessing to be a case of knowledge. Finally, I consider the relation between the trial
openaire +2 more sources
I analyse Theaet. 200e-201c. I hold that this passage provides specific insights into: first, the nature of sensible things and events; second, the nature of knowledge. I show that the text should be taken as an analogy, which means that Plato does not consider eye-witnessing to be a case of knowledge. Finally, I consider the relation between the trial
openaire +2 more sources
The Objectives of a Randomised Controlled Trial
1983A trial may be conceived to test more than one hypothesis but it is good practice to determine one or a limited set of major objectives. For example, an investigator may be interested in a trial of a new antihypertensive drug in elderly patients. The major objective could be either to demonstrate the efficacy of the drug in lowering blood pressure or ...
openaire +1 more source
Rationale, objectives, and interpretation of randomized controlled trials
Journal of Clinical Apheresis, 1997A randomized controlled trial (RCT) is the most definitive tool for evaluation of the effectiveness of an intervention and can establish a cause-and-effect relationship between an intervention and an improved disease outcome. However, the undertaking of an RCT does not guarantee valid results, and the findings of RCTs of the same intervention are often
openaire +2 more sources
III. Trial of modifications to Eurospin MRI test objects
Magnetic Resonance Imaging, 1993The original design of the Eurospin test objects (Magn. Reson. Imaging 6:195-199; 1988) for the assessment of magnetic resonance imaging (MRI) image quality, was subjected to re-evaluation at several meetings during the subsequent years, culminating in some changes to the designs.
openaire +2 more sources
Multiplicity Issues in Clinical Trials With Multiple Objectives
Statistics in Biopharmaceutical Research, 2013Modern clinical trials for evaluating efficacy and safety of new treatments frequently include multiple objectives with questions of varying clinical importance. Answering them generally requires performing a number of statistical tests and analyses which raise multiplicity of tests issues.
Mohammad F. Huque +2 more
openaire +1 more source