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Surgical Trial: Possibilities and Objections
European Surgical Research, 2008Trials are widely regarded as the best method for assessing the effectiveness of new techniques. The placebo effect of surgery is a real but little considered fact; other problems that arise in surgical trials are the skills of the participating surgeons, the random assignment of patients and the impossibility of a wholly blind approach.
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Applications of covering principle to clinical trials with multiple objectives
Communications in Statistics - Simulation and Computation, 2021A novel covering principle was recently proposed to address the multiplicity issue in the multiple hypotheses testing with a hierarchical structure.
Hong Zhou, Huajiang Li
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The Trials of the Gas Mask An Object of Fumbling
Diogenes, 1993It was during the Gulf War that I discovered the gas mask to be an object. As it became increasingly credible and imminent, the unfathomable menace was crucially rescaled to the toxic potency and dispersal pattern of law-abiding molecules. So it went with the gas mask: the Gulf War transformed it from a vaguely morbid mental image into a facial object ...
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Superchain procedures in clinical trials with multiple objectives
Statistics in Medicine, 2012This paper introduces a new class of multiple testing procedures for addressing multiplicity problems arising in clinical trials with multiple objectives grouped into families. The families may correspond to equally important sets of objectives (co‐primary endpoints) or ordered sets of objectives (primary and secondary endpoints).
Kordzakhia, George, Dmitrienko, Alex
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