Results 121 to 130 of about 104,393 (315)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Gurdjieff and C. G. Jung: Life Is Real Only Then, When ‘I Am’ and the Question of Individuation
Correspondences, 2020 The third part of Gurdjieff’s trilogy All and Everything has not been studied sufficiently or earned any considerable attention by scholars. Its structure seems rather incoherent and circumstantial and its overall message diffused and centerless. However,
Vrasidas Karalis
doaj
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Forum: Qualitative Social Research, 2011 The adoption of a rigorous experimentalism in the discipline of psychology has imposed tight constraints on what can be asked in psychological research and what sorts of answers given.
Jeffery Yen, Romin W. Tafarodi
doaj
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Objectivity Rehabilitated [Chapter 5 of Objectivity]
, 2015 In Part II we primarily studied the key philosophical concept of objectivity through its applications in methodologically divergent fields like those of the natural and behavioral sciences, and. In Part III we will take a different approach and primarily
Axtell, Guy
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
, 2013 Objectivity became one of the central defining principles of scientific psychology, its purpose to achieve value neutrality and knowledge untainted by the preferences of those who produce knowledge.
Hollway, Wendy
core
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Objectivity revisited: Objectivity in Journalism, by Steven Maras
Church, Communication and Culture, 2019 Norberto González Gaitano
doaj +1 more source