Results 41 to 50 of about 104,393 (315)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

OBJECTIVITY VERSUS TRUTH

open access: yesDaimon, 2001
El propósito de este artículo es clarificar la diferencia entre la ciencia que se practica en un mundo dividido entre lo verdadero y lo falso y la que tiene lugar en un espacio que divide lo objetivo de lo subjetivo.
Lorraine Daston
doaj  

War Journalism and 'Objectivity' [PDF]

open access: yesConflict & Communication Online, 2006
This article opens by considering an apparent paradox. Many professional journalists, working on many media in many countries, consider themselves 'objective'.
Annabel McGoldrick
doaj  

Scientists’ situated knowledge: Strong objectivity in transdisciplinarity [PDF]

open access: yes, 2015
Although transdisciplinary research has started addressing important epistemological challenges, as evidenced by the discussion about ‘mode 2’ knowledge production, its relation with postulations of ‘scientific objectivity’ is not yet well clarified.
Rosendahl, Judith   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Object disappearance for object discovery [PDF]

open access: yes2012 IEEE/RSJ International Conference on Intelligent Robots and Systems, 2012
A useful capability for a mobile robot is the ability to recognize the objects in its environment that move and change (as distinct from background objects, which are largely stationary). This ability can improve the accuracy and reliability of localization and mapping, enhance the ability of the robot to interact with its environment, and facilitate ...
Julian Mason   +2 more
openaire   +1 more source

Internal auditor’s objectivity threats: an exploratory study in Malaysia [PDF]

open access: yes, 2016
Recently, there has been a growing criticism on the internal audit profession for the failure to discharge their responsibility as independent assurers diligently.Amongst the root causes that contribute to the flaws in internal audit judgment is the ...
Mohd Razali, Fazlida   +2 more
core  

The epistemological problem of the objectivity of knowledge

open access: yes, 2017
The problem of the objectivity of knowledge arises in scientific research, but it is not exclusive of scientific disciplines. The paper analyzes therefore the problem of human knowledge from the point of view of its intrinsic objectivity. From this point
minazzi fabio
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

THREAT TO FREE INFORMATION AND FREEDOM OF INFORMATION [PDF]

open access: yesCES Working Papers, 2010
“Imagine a world in which every single person on the planet is given free access to the sum of all human knowledge. That’s what we’re doing.” At a time when internet access is widely available, information is spread around the globe rapidly.
Ulrich Müller
doaj  

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