Results 61 to 70 of about 133,108 (299)
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2015 Purpose. Based on the understanding of The New Time philosophy as a response to the challenges of the era in relation to the construction of an objective picture of the world and the self-creation of man, to analyze the main options for evaluating the ...
Anatolii Malivskyi
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Evaluating Authenticity in Heritage: A Quantitative Framework
Ochrona Dziedzictwa KulturowegoAuthenticity has long been regarded as an essential criterion for valuing heritage. While the Venice Charter presents a paradigm for international conservation policies aimed at general heritage protection, the Nara Document advances this by emphasizing ...
Ayesha Agha Shah +2 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Valid knowledge of performance provided by a motion capturing system in shot put
Frontiers in Sports and Active LivingExtended feedback on knowledge of performance in sports techniques is very challenging and requires a high level of expertise. This poses a significant problem for experiments on providing extended feedback, as it is essential to ensure that the “correct”
Stefan Künzell +2 more
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
ExchangesSubjective formulation of research culture drives momentum for positive person-centred change. A common articulation is one, which emphasises cultural problems arising from overemphasis of the ‘lone academic’, exploitation of ‘lesser-academics’ and ...
Robert Pilling
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The epistemological problem of the objectivity of knowledge
, 2017 The problem of the objectivity of knowledge arises in scientific research, but it is not exclusive of scientific disciplines. The paper analyzes therefore the problem of human knowledge from the point of view of its intrinsic objectivity. From this point
minazzi fabio
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
, 2013 Objectivity became one of the central defining principles of scientific psychology, its purpose to achieve value neutrality and knowledge untainted by the preferences of those who produce knowledge.
Hollway, Wendy
core +5 more sources