Results 71 to 80 of about 133,108 (299)
Philosophies, 2019 This essay discusses current research efforts in conversational systems from the philosophy of science point of view and evaluates some conversational systems research activities from the standpoint of naturalism philosophical theory.
Tosin P. Adewumi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
KADI ABDULCEBBAR'DA VE KİERKEGAARD'DA KORKUNUN TEOLOJİSİ
Felsefe Dünyası, 2010 Kadı Abdulcebbar ve Kierkegaar'da Korkunun Teolojisi.
İbrahim Arslan
doaj
História, Ciências, Saúde: Manguinhos, 2008 O ultra-som obstétrico sofreu uma transformação peculiar no Brasil, sendo uma tecnologia de imagem médica que progressivamente transformou-se em uma modalidade de 'consumo' e 'lazer'.
Lilian Krakowski Chazan
doaj +1 more source
Advocacy and Objectivity in Science [PDF]
Three strategies for scientific research in management are examined: advocacy, induction, and multiple hypotheses. Advocacy of a single dominant hypothesis is efficient, but biased. Induction is not biased, but it is inefficient.
JS Armstrong
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Social Space and the Question of Objectivity / Der soziale Raum und die Frage nach der Objektivität
Gestalt Theory, 2017 In speaking of the social dimensions of human experience, we inevitably become involved in the debate regarding how they are to be studied. Should we embrace the first-person perspective, which is that of the phenomenologists, and begin with the ...
Mensch James
doaj +1 more source
Adaptive Objectness for Object Tracking
IEEE Signal Processing Letters, 2016 Object tracking is a long standing problem in vision. While great efforts have been spent to improve tracking performance, a simple yet reliable prior knowledge is left unexploited: the target object in tracking must be an object other than non-object.
Pengpeng Liang +4 more
openaire +2 more sources
The Objectivity of Moral Judgements [PDF]
, 2006 The problem I wish to address is one that is widespread in analytic moral philosophy viz., that of transcending individuality in an attempt to develop theories and arguments that generally explain what occurs when we make moral judgements.
Brockless, Adrian
core