Results 91 to 100 of about 508,289 (303)

SOME ASPECTS ABOUT THE LIFE OF GREATEST FEMALE ENTREPRENEUR IN AMERICAN HISTORY, MARY KAY ASH [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2009
The gender and enterprise research field is perhaps more accurately portrayed as under-developed. Despite a growing enthusiasm among researchers and policy makers to focus an issues relating to gender and enterprise, and a marked increase in the number ...
Negrusa Adina Letitia   +1 more
doaj  

Speaker self-profiling through discursive indexation and syntactic encoding in Spanish radio talk

open access: yesBorealis: An International Journal of Hispanic Linguistics, 2017
Syntactic and discursive choices in context can constitute resources for the interactional profiling of the direct participants. This study analyzes the frequencies with which speakers index themselves, as well as the syntactic functions they preferably ...
Miguel A. Aijón Oliva
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Is Subjectivity Possible - the Post-Modern Subject in Legal Theory [PDF]

open access: yes, 1991
This article puts forward a thesis and then attempts to prove (or at least to develop) that thesis in two related areas. The thesis is that legal theory in general, and critical legal theory in particular, has concentrated too much on critiques of ...
Boyle, James
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Injonction à la transparence dans le fact-checking : de l’idéal de l’objectivité à une tentative de proximité

open access: yesSociologies, 2020
Our contribution examines how Brazilian online media specialized in fact-checking mobilize transparency in their discursive productions during the period of the last presidential campaign (2018).
Lorreine Petters
doaj  

Kantowska metafizyka percepcji (Kant’s Metaphysics of Perception) [PDF]

open access: yesAnaliza i Egzystencja, 2009
This article treats of an issue of Kant’s the metaphysics of perception as a specific sphere where concept of sense perception within transcendental philosophy seem to be rooted into a wider context of metaphysical presuppositions. The text is an epitome
Paweł Sikora
doaj  

Advocacy and Objectivity in Science [PDF]

open access: yes
Three strategies for scientific research in management are examined: advocacy, induction, and multiple hypotheses. Advocacy of a single dominant hypothesis is efficient, but biased. Induction is not biased, but it is inefficient.
JS Armstrong
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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