Results 51 to 60 of about 20,287 (302)

Does the International Court of Justice resist defining the contours of unilateral acts? Reflections in the light of his pronouncement on the issue o f the obligation to negotiate access to the Pacific Ocean (Bolivia v. Chile) [PDF]

open access: yes, 2021
Con ocasión del pronunciamiento la Corte Internacional de Justicia (cij) en el asunto de la obligación de negociar el acceso al océano Pacífico, que enfrentó a Bolivia contra Chile, se perdió una magnífica oportunidad para definir los difusos contornos ...
Tremolada Álvarez, Eric
core   +1 more source

A preliminary reference to the CJEU focusing on the consequences of a breach of the obligation to refer it [PDF]

open access: yes
1 A preliminary reference to the CJEU focusing on the consequences of a breach of the obligation to refer it Jan Rampas Abstract The primary topic of the dissertation is whether the right to effective judicial protection under Article 47 of the Charter ...
Rampas, Jan
core   +3 more sources

The Questions That Never Came: How National Judges Use Their Discretion in the Preliminary Ruling Procedure

open access: yesEuropean Journal of Empirical Legal Studies
While domestic judges ultimately decide whether to refer questions to the Court of Justice of the European Union (CJEU), little is known about how the idea to refer is introduced in national litigation or about the decision (not) to refer.
Isak Nilsson
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Good, bad and ugly genes? Science matters, also in terms of terminology and word usage

open access: yesOpen Psychology, 2021
Our words shape our thinking, our thinking creates action. Scientific terms can be particularly influential when used in everyday language in terms of allegedly scientific arguments that back certain views or actions.
Carbon Claus-Christian
doaj   +1 more source

Calibrating states' emissions reduction due diligence obligations with reference to the right to life

open access: yesReview of European, Comparative & International Environmental Law, 2022
AbstractThe 2017 Advisory Opinion of the Inter‐American Court of Human Rights broke new ground in finding that States' failure to regulate with due diligence the activities taking place within its territory could constitute a breach of the human rights of persons located elsewhere.
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Moral obligation and the ethics of virtue [PDF]

open access: yes, 1982
For almost a quarter-century now much has been made of so-called virtue ethics. G.E.M. Anscombe and Philippa Foot have been among the leaders of a contemporary movement away from "law-like" ethics and toward a conception of ethics in which ...
Pool, Frank Thomas
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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