Results 61 to 70 of about 20,287 (302)
H. L. A. Hart on Legal and Moral Obligation [PDF]
, 1974 One of the central problems in both moral and legal philosophy has been to offer a satisfactory analysis of the concept of obligation. In ordinary language the word obligation is used in several different contexts. It may refer to moral obligation (e.g.
Michigan Law Review
core +1 more source
Tobacco industry:a barrier to social justice [PDF]
, 2022 Social justice recognises the need for the ‘the distribution of wealth, opportunities, and privileges within a society’. According to the United Nations, social justice is an underlying principle for peaceful and prosperous coexistence within and among ...
Laurent Huber +10 more
core +1 more source
Nigerian Radiographers Obligation to Diagnostic Reference levels (DRLs) in Medical Imaging
Journal of Radiography and Radiation Sciences, 2020 Background: Diagnostic reference levels (DRLs) help to identify unusually high dose levels in medical procedures involving radiation. This will subsequently, stimulate quality control. There are legislations and guidelines requiring the Member States of the European Union to adopt DRLs.
openaire +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Humanity, Obligation, and the Good Will: An Argument against Dean's Interpretation of Humanity [PDF]
, 2010 Humanity (die Menschheit) is an important notion within Kant's moral theory. The humanity formulation of the categorical imperative (FH) commands: ‘So act that you use humanity, whether in your own person or in the person of any other, always at the same
Lara Denis
core +1 more source
FISCAL AND ACCOUNTING ASPECTS RELATED TO THE RESULTS OF THE INVENTORY [PDF]
Buletin ştiinţific: Universitatea din Piteşti. Seria Ştiinţe Economice, 2019 The paper aims at highlighting the importance of inventory in assuring the integrity of the assets and presenting the real situation of assets, equity and debt.
Marcela BENGESCU
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source