Results 61 to 70 of about 552,453 (312)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Genealogy of Early Islamic Traditions: A Study of Hadith on the Honour of Time [PDF]

Pharos Journal of Theology
This research addresses the genealogy of early Islamic traditions with a focus on the study of hadith traditions which refer to a collection of traditions containing utterances of the prophet Muhammad which, along with accounts of his daily practice (the
Revi Fauzi Putra Mina, Vivi Adryani Nasution, All Rizky Ramadhan   +2 more
doaj   +1 more source

The Questions of Authority [PDF]

, 1992
In 1992, Professor, Frederick Schauer of Harvard University, delivered the Georgetown Law Center’s twelfth Annual Philip A. Hart Memorial Lecture: Two Cheers for Authority: Should Officials Obey the Law?.
Schauer, Frederick
core   +1 more source

A State Preferences Account of Customary International Law Adjudication [PDF]

, 2014
The standard account today of customary international law (CIL) is that it arises from the widespread and consistent practice of states followed out of a sense of legal obligation.
Bradley, Curtis A.
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

The fire of San Miguel prison: It’s veredict of acquittal and the international obligation to protect the involved human rights

Anuario de Derechos Humanos, 2015
This article presents arguments about the international responsibility of the Chilean State derived from the fire occurred in the San Miguel Prison, in which 81 internees died and other 13 result severely injured.
Karinna Fernández Neira, Nancy García Fregoso   +1 more
doaj   +1 more source

Jeremy Bentham, social criticism and levels of meaning [PDF]

, 2003
Published in an e ...
Tyler, C.
core  

OWL-POLAR : semantic policies for agent reasoning [PDF]

, 2010
The original publication is available at www.springerlink ...
A. Elhag, A. García-Camino, C. Castelfranchi, E. Lupu, E. Sirin, G. Boella, G. Sartor, H. Hill, H. Zhao, J. Patel, J.D. Ullman, M. Sloman, M.J. Kollingbaum, P. Haase, W.W. Vasconcelos   +14 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Event-Clock Nested Automata

, 2017
In this paper we introduce and study Event-Clock Nested Automata (ECNA), a formalism that combines Event Clock Automata (ECA) and Visibly Pushdown Automata (VPA). ECNA allow to express real-time properties over non-regular patterns of recursive programs.
Bozzelli, Laura, Murano, Aniello, Peron, Adriano   +2 more
core   +1 more source