Results 101 to 110 of about 1,421,323 (343)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Europe's Journal of Psychology, 2015 This paper focuses on the effects of activating expected self as compared to the effects of activating the ought self. The expected self is a component of self-knowledge that pertains to the perception of one’s capabilities and potentials.
Waclaw Bak +2 more
doaj +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Implementasi Kewajiban Notaris untuk Melekatkan Sidik Jari Para Penghadap pada Minuta Akta
SASI, 2019 The unclear setting regarding the notary's obligation to attach the fingerprints of the viewers influences the implementation of these provisions. There is a vagueness of norms against the provisions of Article 16 paragraph (1) letter c UUJN-P because ...
Rizka Rahmawati
doaj +1 more source
Extraterritorial Obligations and the Obligation to Protect
, 2017 Since the late 1970s, what we today label ‘globalisation’ has altered many aspects of international law, not least international human rights law. This has been reflected inter alia in increased calls for universal respect for human rights beyond a state’s territorial border.
openaire +2 more sources
Why Proximity Matters for the Concept of Supererogation [PDF]
, 2017 The concept of supererogation is strictly correlated with duty, since its peculiar value is defined by acts that go beyond our regular obligations.
Grigoletto, Simone
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
The Hidden Effect of Rules: Behavioural consequences of Obligations [PDF]
How formal institutions (e.g. laws and public policies) affect human behaviour represents a crucial issue in economic analysis. Formal rules are defined as obligations backed by incentives. The economic literature has largely studied the role of material
Pietro Vertova, Roberto Galbiati
core
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Audit of Fiscal Obligations at Economic Entities from Romania
Journal of Danubian Studies and Research, 2020 The audit of fiscal obligations, or the fiscal audit, as it is also called in the specialized literature, can be considered both as an integral part of the financial audit of the annual financial statements, and as an independent audit.
Daniel Marius Moscu
doaj