Results 81 to 90 of about 336,462 (290)

A Comparison with Analysis of the SADC FIP before and after Its Amendment

open access: yesPotchefstroom Electronic Law Journal, 2017
Discourses on rights, duties and obligations predominantly take place within the context of constitutional, administrative and human rights law.
Tinashe Kondo
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Financing Agreements [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī, 2014
In the business world, one of the most important issues is how to provide finance for business enterprises. Factoring as one of the common ways of financing through account receivable is used to finance small and medium enterprises.
Gholam nabi Fayzi chekab, ALI Darzi
doaj  

Entitlements and Obligations [PDF]

open access: yes, 1998
AbstractMarket interactions are brought about by the interplay of entitlements and obligations. Entitlements are rights, as perceived by the individuals. They are subjectively perceived rights that go along with a motivational disposition to defend them. Obligations are the counterparts of entitlements.
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

To What Do We Have Moral Obligations and Why? II

open access: yes, 1985
Following up on his 1 June 1985 article on moral obligations to living human beings versus other sentient beings, Gillon focuses on arguments for and against prohuman "speciesism," the claim that "viability" is a justifiable criterion for differentiating
Gillon, Raanan
core   +1 more source

DEVELOPMENT OF THE CONCEPT OF SUBSIDIARY LIABILITY AS A TOOL TO INCREASE THE EFFECTIVENESS OF THE INSTITUTION OF BANKRUPTCY AND ENSURE THE ECONOMIC SECURITY OF THE COUNTRY

open access: yesМодернизация, инновация, развитие, 2018
Purpose: the main purpose of the article is to investigate modern problems of the institution of bankruptcy and the impact of its results on the system of economic security of the state, to develop recommendations for improving the institution of ...
V. N. Alferov, M. M. Korigova
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Impacts of Early Childhood Education Social Obligations on Families and Whanau [PDF]

open access: yes, 2014
This thesis explores the impacts of ECE social obligations on affected families and whānau. In 2013 ECE social obligations were introduced through the Social Security (Benefit Categories and Work Focus) Amendment Bill.
Randall, Judith
core  

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