Results 71 to 80 of about 336,462 (290)

The military obligations of the English people 1511-1558 [PDF]

open access: yes, 1955
PhDThis thesis is concerned with the military obligations of the people of England in the period between the re-issue of the Statute of Winchester in 1511 and its repeal in 1558. In its pages an attempt is made to discover what these obligations were
Goring, John Jeremy
core   +4 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Principles on climate obligations of enterprises

open access: yes, 2017
Climate change is the most important challenge humankind has ever faced. It is commonly accepted that greenhouse gas (GHG) emissions must be reduced at great pace and to a significant extent to keep global warming below 2 (or, preferably, 1.5) degrees ...
Expert Group on Climate Obligations of Enterprises
core  

Airport operator and aircraft operator in case of bird strike. Relations, obligations and liability [PDF]

open access: yesTransport Problems, 2011
Air transport is subject to various risks. One of them is bird strike hazard. Despite numerous regulations concerning prevention from this type of occurrence, it is not possible to eliminate them entirely.Bird strikes most often take place during take ...
Sylwia KACZYŃSKA-ADAMCZYK
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Set-off as a way of ending obligations [PDF]

open access: yesGlasnik Advokatske komore Vojvodine, 2015
In this work the authors analyzed set-off as one of the most common and most significant way of ending obligations in our legal system. The most important and in practice the most common way of ending obligations is their fulfillment.
Radovanov Aleksandar, Danojlić Miladin
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Analyzing the Principles of Behavior Set Out in the Code of Ethics for Public Officials and in the Canons of Islam

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки
This article analyzes the norms of behavior in the Russian public service and Islam. A comparative and structural study of the behaviors typical of public officials and Muslims was carried out.
G. N. Shavalieva
doaj   +1 more source

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