Results 101 to 110 of about 1,590,564 (275)

TMAC: a Transformer-based partially observable multi-agent communication method [PDF]

open access: yesPeerJ Computer Science
Effective communication plays a crucial role in coordinating the actions of multiple agents. Within the realm of multi-agent reinforcement learning, agents have the ability to share information with one another through communication channels, leading to ...
Xuesi Li   +3 more
doaj   +2 more sources

SpecBit, DecayBit and PrecisionBit: GAMBIT modules for computing mass spectra, particle decay rates and precision observables [PDF]

open access: diamond, 2018
Peter Athron   +12 more
openalex   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

A Deep Hierarchical Reinforcement Learning Algorithm in Partially Observable Markov Decision Processes

open access: yesIEEE Access, 2018
In recent years, reinforcement learning (RL) has achieved remarkable success due to the growing adoption of deep learning techniques and the rapid growth of computing power.
Tuyen P. Le   +2 more
doaj   +1 more source

Data Fusion of Observability Signals for Assisting Orchestration of Distributed Applications [PDF]

open access: gold, 2022
Ioannis Tzanettis   +4 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Observable-driven speed-ups in quantum simulations

open access: yesCommunications Physics
Quantum simulation represents a cornerstone application for quantum computers, offering the potential to solve classically intractable problems in physics, chemistry, and materials science. Despite being one of the most accessible simulation methods, the
Wenjun Yu, Jue Xu, Qi Zhao
doaj   +1 more source

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