Results 51 to 60 of about 343,769 (301)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analysis of Novel Basketball Coaches: Pedagogical Content Knowledge Using Mixed Methodology

open access: yesFrontiers in Psychology, 2022
The aim of this article is to know the role of learning tasks within the pedagogical content knowledge (PCK) of novel sports coaches in initial stages of sports training of children/young people and their impact on their daily work.
Juan Granda-Vera   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Scientific methodology. Analytical observational studies

open access: yes, 2023
20.500.12530/87855Observational and analytical epidemiological studies are those that allow the study of causal relationships and associations between variables, without the researcher assigning or introducing the study factor into the sample.
Marcos Alonso García   +3 more
core   +1 more source

Analysis of the internal logic of breaking using temporal and sequential parameters [PDF]

open access: yes, 2023
Quantifying the effort of a sport confrontation by determining its temporal structure concerns the scientific community. It has not yet been studied in breaking.
Prieto Lage, Iván   +2 more
core   +1 more source

Systematic observation in the technical evaluation of canoe paddling: design of an observational tool

open access: yesE-balonmano.com: Revista de Ciencias del Deporte
Technical precision during the paddling gesture is a fundamental element for sports performance in canoeing. Therefore, its evaluation and analysis are a primary objective for athletes in this discipline.
Juan Pablo Morillo-Baro   +5 more
doaj   +1 more source

Movement Notation Revisited: Syntax of the Common Morphokinetic Alphabet (CMA) System

open access: yesFrontiers in Psychology, 2018
Advances in the study of non-verbal behavior and communication have generated a need for movement transcription systems capable of incorporating continuous developments in visual and computer technology.
Conrad Izquierdo, M. Teresa Anguera
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Diachronic analysis application for the detection of soccer performance standards: a case study

open access: yesInternational Journal of Computer Science in Sport, 2020
The purpose of this study is to analyse the interactions established by Gerard Piqué, one of the world’s top defenders, within the general context of the team.
Maneiro R, Amatria M, Anguera MT
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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