Results 191 to 200 of about 1,004,406 (261)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

An AI-powered Bayesian Generative Modeling Approach for Causal Inference in Observational Studies. [PDF]

J Am Stat Assoc
Liu Q, Wong WH.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

From Theory to Practice: GPT-Supported Data Extraction in Observational Studies on Transcatheter Aortic Valve Replacement. [PDF]

JACC Adv
Brigiari G, Dotto R, Cernetti C, Gregori D, Lorenzoni G.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Frailty status and the risk of dementia, Alzheimer's disease: a meta-analysis of observational studies. [PDF]

Front Neurol
Zhao Y, Zeng M, Zhang S, Peng D.
europepmc   +1 more source

Leveraging Data Science for Conducting Observational Studies: Highlighting Advantages and Limitations Throughout the Evaluation of a Use Case. [PDF]

Mayo Clin Proc Digit Health
Rios-Duarte JA, Pick TL, Robson TN, Lin RJ, Todd A, Romero-Brufau S, Vidal NY.   +6 more
europepmc   +1 more source

Sarcopenia as an independent associated factor for urinary incontinence in adults: a systematic review and meta-analysis of observational studies. [PDF]

BMC Geriatr
Guo Z, Huang L, Chen J, Wang Z, Tang G, Li Y, Bai Z, Pan J.   +7 more
europepmc   +1 more source

Correction: Repeat procedures after pulsed field ablation for atrial fibrillation: tertiary centre experience and meta-analysis of observational studies. [PDF]

J Interv Card Electrophysiol
Ha FJ, Paitry S, Prinsloo D, Han HC, Brown AJ, Nerlekar N, Kotschet E.   +6 more
europepmc   +1 more source

Performance of propensity score methods in observational studies: a systematic review. [PDF]

Syst Rev
Tatari M, Rosato S, D'Errigo P, Jona Lasinio G.   +3 more
europepmc   +1 more source