Results 61 to 70 of about 1,037,282 (261)

Type 1 diabetes and the risk of epilepsy: A meta‐analysis

Journal of Diabetes Investigation
Aims/Introduction An overrepresentation of epilepsy has been suggested in patients with type 1 diabetes (T1D). This meta‐analysis was conducted to evaluate if type 1 diabetes is associated with a higher incidence of epilepsy.
Shuhui Wu, Yanan Ding
doaj   +1 more source

STROBE, CONSORT, PRISMA, MOOSE, STARD, SPIRIT, and other guidelines – Overview and application

Saudi Journal of Anaesthesia
The purpose of research is to seek answers and new knowledge. When conducted properly and systematically, research adds to humanity's corpus of knowledge and hence to our general advancement.
Victor Grech, Abdelazeem A Eldawlatly
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Study characteristics of cohort studies (observational studies & retrospective studies).

, 2022
Study characteristics of cohort studies (observational studies & retrospective studies).
Malavalli Siddalingegowda Srikanth (13170357), Subramanian Ramaswamy (1856344), Madhan Ramesh (13170354), Teggina Math Pramod Kumar (13170360), Niharika Pathakamuri (13170351), Sujit Kumar Sah (13170345), Atiqulla Shariff (13170348), Krishna Undela (129851)   +7 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Higher potency statins and the risk of new diabetes: multicentre, observational study of administrative databases

, 2018
Objective: To evaluate the incremental increase in new onset diabetes from higher potency statins compared with lower potency statins when used for secondary prevention. Design Eight population based cohort studies and a meta-analysis.
Rahme, Elham, Paterson, J. Michael, James, Matthew T., Tamim, Hala, Lipscombe, Lorraine, Raymond, Colette B., Filion, Kristian B., Dormuth, Colin R., Teare, Gary F.   +8 more
core   +1 more source

‘Quality in, quality out’, a stepwise approach to evidence-based medicine for rare diseases promoted by multiple endocrine neoplasia type 1

Endocrine Connections, 2018
Rare diseases pose specific challenges in the field of medical research to provide physicians with evidence-based guidelines derived from studies with sufficient quality.
Dirk-Jan van Beek, Rachel S van Leeuwaarde, Carolina R C Pieterman, Menno R Vriens, Gerlof D Valk   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Observational studies (secondary meta-analysis).

, 2023
(1) Overview of participant demographics and injury characteristics for the pooled observational studies. (2) Summary of the individual studies included in the review.
Carole Lunny (769209), Daniel D. Hodgkiss (17458593), Andrei V. Krassioukov (5704454), Shin-Yi Chiou (448775), Matthias Walter (820008), Tom E. Nightingale (4495174), Samuel J. E. Lucas (10584224), Gurjeet S. Bhangu (17458596), Catherine R. Jutzeler (8280150)   +8 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source