GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille +6 more
wiley +1 more source
Evaluating the Association Between PPI Use and Dementia Risk Considering Methodological Choices: An Updated Meta-Analysis. [PDF]
Ha H +5 more
europepmc +1 more source
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source
GLP-1 receptor agonists in systemic lupus erythematosus: a scoping review. [PDF]
Sia R, Ting EL, Choy SW, Oon S.
europepmc +1 more source
Ethical Foreground and Background in Adult Educator Work
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley +1 more source
Prestorage Leukoreduction of Canine Blood Products: A Critically Appraised Topic. [PDF]
Proverbio D, Perego R, Spada E.
europepmc +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Editorial: Innovative personalized medicine strategies for managing multi-morbidity. [PDF]
Shukla P +3 more
europepmc +1 more source
Transforaminal versus interlaminar endoscopic lumbar discectomy for L5-S1 lumbar disc herniation: meta-analysis. [PDF]
Shi H +6 more
europepmc +1 more source

