Results 191 to 200 of about 2,471,157 (341)

Observation in a treatment-free remission in chronic myeloid leukemia patients with a stable deep molecular response in the Russian portion of the international multicenter population based study EUTOS PBS

, 2022
Ekaterina Chelysheva, О. В. Лазарева, Anna Turkina, Olga Vinogradova, Л В Гаврилова, M. V. Galayko, Dolgorzhap Dasheeva, А. С. Лучинин, Sergey Meresiy, О. М. Сендерова, А. А. Шутылев, A. A. Kulikovskiy, С. М. Куликов   +12 more
openalex   +2 more sources

An observational study of asymmetry in CMT1A [PDF]

, 2015
Carr, AS, Laura, M, Pelayo-Negro, AL, Reilly, MM, Skorupinska, M   +4 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Differences in the Phenotype of Bacterial and Viral Sepsis-A Prospective, Multicenter, Observational Study. [PDF]

Viruses
Perschinka F, Lehner GF, Mayerhöfer T, Köhler A, Hasibeder W, Krismer C, Killian J, Fries D, Bösch J, Perschinka N, Hohenauer P, Perschinka N, Hackl AL, Joannidis M.   +13 more
europepmc   +1 more source

National roll-out of social prescribing in England's primary care system: a longitudinal observational study using Clinical Practice Research Datalink data

Feifei Bu, Alexandra Burton, Naomi Launders, Amy E. Taylor, Alvin Richards‐Belle, Stephanie Tierney, David Osborn, Daisy Fancourt   +7 more
openalex   +1 more source

The Last Year Before Graft Failure Negatively Impacts Economic Outcomes and is Associated With Greater Healthcare Resource Utilization Compared With Previous Years in the United Kingdom: Results of a Retrospective Observational Study [PDF]

, 2019
Gorden Muduma, Varuna Aluvihare, Marc Clancy, Enrico De Nigris, Carolyn Whitlock, Margarita Landeira, Jameel Nazir   +6 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Potential pitfalls in observational study designs

Southwest Respiratory and Critical Care Chronicles, 2016
Phillip Watkins
doaj  

Electrocardiographic Abnormalities in Patients With Leptospirosis: A Clinical Observational Study. [PDF]

Cureus
Pranav B K, Adalarasan S, S Y, Nikesh P, C H.   +4 more
europepmc   +1 more source