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Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study) [PDF]
, 2013 Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high.Pereira Junior, Gerson Alves, Pereira GA, El Zalabany T., Tugnoli G, Yuan, Kuo-Ching, Ishii W., Massalou D, Jovine, Elio, Abbas A., Malangoni M., Sartelli M, Guercioni G, di Saverio S., Balogh Z, Trana C., Kok K. Y. Y., di Saverio S, Wataru Ishii, Marwah S, Rajeev Sharma, Sartelli M., Carlos Augusto Gomes, Attri AK, Elia Poiasina, Sanjuan, Juan, Kong V., Massalou, Damien, Ordonez, Carlos, Zsolt Balogh, Boonying Siribumrungwong, Norio Sato, di Saverio, Salomone, Ansaloni L, Jovine E., Irahara, Takayuki, Sanjuan J, BAIOCCHI, Gian Luca, Alberto Tavares, Offir Ben-Ishay, Ben Ishay O, Luca Ansaloni, Shoko T, Jae Gil Lee, Bendinelli, Cino, Carlos Ordonez, Bendinelli C, Mefire AC, Boris Sakakushev, Suk-Kyung Hong, Baiocchi, Gianluca, Zachariah S, Tomohisa Shoko, Bendinelli C., Kluger Y, Gerych, Ihor, Gupta S, Kong, Victor, Attri A, Velmahos G, Irahara T., Ernest Moore, Salomone di Saverio, Peev MP, Lohsiriwat V, Khalifa K. A., Velmahos, George, Hong, Suk-Kyung, Walter Biffl, Hamedelneel, Ahmed O, Sato N, Rita Barnabé, Siribumrungwong B., Augustin, Goran, Biffl W, Khalifa, Khalid Al, Gerson Alves Pereira Junior, Wagih Ghnnam, Ahmed O Hamedelneel, Biffl W., Helmut Alfredo Segovia Lohse, Agresta F, Ferdinando Agresta, Gerych I., Mefire, Alain Chichom, Kok KY, Segovia Lohse HA, Skrovina M, Varut Lohsiriwat, Gupta, Sanjay, Siribumrungwong B, Ahmed A., Lee JG, Juan Sanjuan, Skrovina M., Kluger Y., Kobe Y., Zachariah, Sanoop, Malangoni, Mark, Kok KYY, Sharma R, Yoshiro Kobe, Moore E., Skrovina, Matej, Poiasina E., Zida M, Jovine E, Gupta S., Marwah, Sanjay, Poiasina, Elia, Díaz Nieto R, Leppaniemi A., Kenneth Yuh Yen Kok, Velmahos G., Khokha, Vladimir, Gomes CA, Ahmed, Adamu, Adesunkanmi A. R. K., Ashraf Abbas, Sakakushev B, Gonsaga RAT, Kenig J., Barnabé, Rita, Coimbra R., Sanjuan J., Sanjay Gupta, Ghnnam, Wagih, Sanjay Marwah, Abbas A, Tranà C, Coccolini F., Barnabe R., Junior G. A. P., Al Khalifa, Khalid, Naidoo, Noel, Gianluca Baiocchi, Tavares A., Victor Kong, Das, Koray, Bala, Miklosh, Kaoru Koike, Agresta F., Sanoop Zachariah, Ricardo Alessandro Teixeira Gonsaga, Moore, Ernest, Díaz-Nieto R, Moore E, Segovia Lohse, Helmut Alfredo, Naidoo N., Kuo-Ching Yuan, Rafael Díaz-Nieto, Ordonez C, Adamu Ahmed, Catena F., Kobe Y, Vettoretto N, AK Attri, Koray Das, Attri, AK, Ari Leppaniemi, Junior, Gerson Alves Pereira, Ishii, Wataru, Adesunkanmi, Abdul Rashid Kayode, Peev M. P., Yunfeng Cui, Kenig, Jakub, Gonsaga RA, Biffl, Walter, Siribumrungwong, Boonying, George Velmahos, Maurice Zida, Sharma R., Ahmed A, Mark Malangoni, Augustin G, Massimo Sartelli, Gonsaga R. A. T., Lohse HA, Murata K., Koike, Kaoru, Tavares A, Sartelli, Massimo, Coimbra, Raul, Hamedelneel AO, Hong SK, Ansaloni, Luca, Tavares, Alberto, Augustin G., Lohse H. A. S., Verni A, Miroslav P Peev, Coccolini, Federico, Guercioni G., Shoko T., Tranà, Cristian, Teixeira Gonsaga, Ricardo Alessandro, Gregorio Tugnoli, Gerych I, Sakakushev B., Koike K, Cui YF, Lohse HAS, Nereo Vettoretto, Sato, Norio, Yuan KC, Elio Jovine, Kok, Kenneth Yuh Yen, Massalou D., Irahara T, Ordonez C., Gonsaga, Ricardo Alessandro Teixeira, Attri, A. K., Damien Massalou, Bala M, Verni, Alfredo, El Zalabany T, Cui Y., Peev, Miroslav P., Gomes, Carlos Augusto, Ben-Ishay O., Adesunkanmi AR, Yuan K. -C., Goran Augustin, Zida, Maurice, Khokha V., Kobe, Yoshiro, Jakub Kenig, Guercioni, Gianluca, Kiyoshi Murata, Vettoretto N., Cui Y, Khokha V, Cristian Tranà, Sato N., Kong V, Gomes C. A., Ishii W, Leppaniemi, Ari, Malangoni M, Marwah S., Kluger, Yoram, Agresta, Ferdinando, 이재길, Naidoo N, Sharma, Rajeev, Vladimir Khokha, Ghnnam W, Noel Naidoo, Junior GA, Balogh Z., Abdul Rashid Kayode Adesunkanmi, Koike K., Gianluca Guercioni, Lee, Jae Gil, Matej Skrovina, Vettoretto, Nereo, Lohse, Helmut Alfredo Segovia, Barnabé R, Balogh, Zsolt, Jarry J, Alain Chichom Mefire, Peev, Miroslav V., Leppaniemi A, Catena, Fausto, Hamedelneel A. O., Raul Coimbra, Verni A., Lohsiriwat, Varut, Zachariah S., Das K., Coccolini F, Jarry, Julien, Hamedelneel, Ahmed O., Khalifa KA, Cino Bendinelli, Cui, Yunfeng, Murata K, Coimbra R, Tugnoli, Georgio, Poiasina E, Sakakushev, Boris, Das K, Federico Coccolini, Alfredo Verni, Lee J. G., Mefire A. C., Diaz-Nieto R., Ben-Ishay O, Murata, Kiyoshi, Al Khalifa K, Shoko, Tomohisa, Adesunkanmi ARK, Ihor Gerych, Jarry J., Chichom Mefire, Alain, Attri A. K., Ben-Ishay, Offir, Zida M., Baiocchi G., Yoram Kluger, Tugnoli, Gregorio, Díaz-Nieto, Rafael, Abbas, Ashraf, Hong S. -K., Catena F, Ghnnam W., Takayuki Irahara, Tamer El Zalabany, Baiocchi G, Kenig J, Ansaloni L., El Zalabany, Tamer, Tugnoli G., Bala M., Lohsiriwat V., Khalid Al Khalifa, Peev, Miroslav P, Fausto Catena, Miklosh Bala, Julien Jarry +318 morecore +1 more sourceExploring the association between exposure to pesticides, polycyclic aromatic hydrocarbons, and phthalates and metabolic syndrome in National Health and Nutrition Examination Survey in the USA, 2007–2012: utilizing a multi-step statistical strategy
BMC Public HealthBackground Pesticides, polycyclic aromatic hydrocarbons (PAHs), and phthalates are recognized as potential contributors to metabolic disorders. Nevertheless, the combined effect of simultaneous exposure to these chemicals on the metabolic syndrome (MetS) Yadan Xu, Yifan Xu, Wen Gu, Xinyi Zhou, Huaying Wu, Xu Yang +5 moredoaj +1 more sourceEnteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld +5 morewiley +1 more sourceReciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.Marie Déborah Bancilhon, Bruno Mesminwiley +1 more sourceMeasuring herpes zoster disease burden in São Paulo, Brazil: a clinico-epidemiological single-center study
Clinics, 2018 OBJECTIVES: Herpes zoster is characterized by acute neuritis and post-herpetic neuralgia. Currently, data concerning the zoster-associated impact on quality of life and healthcare resource utilization in Brazil are scarce.João Toniolo-Neto, Eliofotisti Psaradellis, Angela Karellis, Emmanouil Rampakakis, Talita Y. Rockett, John S. Sampalis, Kelly D. Johnson, Homero A. Monsanto, Camilo J. Acosta +8 moredoaj +1 more sourcePhosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia +3 morewiley +1 more sourceCurrent Status of the Treatment of COPD in China: A Multicenter Prospective Observational Study
International Journal of COPD, 2020 Yuqin Zeng,1– 3 Shan Cai,1– 3 Yan Chen,1– 3 Jiaxi Duan,1– 3 Yiyang Zhao,1– 3 Xin Li,4 Libing Ma,5 Qimi Liu,6 Yingqun Zhu,7 Ming Chen,8 Meiling Zhou,9 Ping Chen1– 3 1Department of Pulmonary and Critical Care Medicine ...Zeng Y, Cai S, Chen Y, Duan J, Zhao Y, Li X, Ma L, Liu Q, Zhu Y, Chen M, Zhou M, Chen P +11 moredoaj