Results 91 to 100 of about 1,473,678 (357)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Background: Low adherence to treatment in Multiple Sclerosis (MS) has been shown to lead to poor health outcomes. Various strategies to improve adherence have been suggested including educative programs, injection devices and dedicated nurse assistance.
Oentrich W +5 more
core +2 more sources
Sleep disturbances and heart failure: observational study and Mendelian randomization study
Introduction Sleep disturbances are prevalent among patients with heart failure (HF) and may trigger acute exacerbations of the condition. However, the causal relationship between sleep disturbances and HF remains uncertain.
Junwen Wang +6 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Osteoarthritis among elderly: cross-sectional study of hospitalization between 2010 and 2022
INTRODUCTION: Osteoarthritis is a common joint disease and one of the main causes of years lived with disabilities as well as one of the reasons for visits to health services.
Aranzazu Cueva-G.Cantón +3 more
doaj +1 more source
Homeopathic Treatment for Chronic Disease: A 6-Year,
Objective: The aim of this study was to assess health changes seen in routine homeopathic care for patients with a wide range of chronic conditions who were referred to a hospital outpatient department.
Mary Ann Liebert, Observational Study
core
Progression of Traumatic Intracerebral Hemorrhage: A Prospective Observational Study
Preliminary evidence has shown that intracerebral hemorrhages, either spontaneous (sICH) or traumatic (tICH) often expand over time. An association between hemorrhage expansion and clinical outcomes has been described for sICH.
Servadei, Franco +13 more
core +1 more source
Are the effects of psychosocial exposures attributable to confounding? Evidence from a prospective observational study on psychological stress and mortality [PDF]
<b>STUDY OBJECTIVES</b> To examine the association between perceived psychological stress and cause specific mortality in a population where perceived stress was not associated with material disadvantage.
Hart, C. +14 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source

