Results 111 to 120 of about 554,337 (247)
Eurasian realignment: Central Asia as a key player in European energy security [PDF]
Wani Ayjaz
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Stereoscopy in Nineteenth Century Brazil: the case of Rio de Janeiro
This study presents a preliminary systematisation of the stereographs that are part of the public collections of Rio de Janeiro. We start with an investigation of the presence of optical devices in nineteenth century Brazil, especially in the city of Rio
Maria Cristina Miranda da Silva
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Es evidente que hoy en día adquiere una importancia singular la visualización de imágenes y también la forma en que ellas -querámoslo o no- impactan nuestra retina, lo cual supone por parte del espectador unos criterios interpretativos que muchas veces ...
Carmen Porta
doaj
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Observer-based numerical schemes
Numerical analysis and control theory are fundamental areas in engineering and applied mathematics. This thesis explores three concepts from control theory used to enhance classical numerical solvers.
AMA Al Hayzea (22000814)
core +3 more sources
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The official newspaper of Stern College for Women and Sy Syms School of BusinessFounded by the women of Yeshiva University's Stern College in 1958, The Observer is the official newspaper representing the student body of Stern College and Yeshiva ...
Kook, Elana (Editor)
core

