Results 111 to 120 of about 554,337 (247)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Stereoscopy in Nineteenth Century Brazil: the case of Rio de Janeiro

open access: yesInternational Journal of Film and Media Arts, 2016
This study presents a preliminary systematisation of the stereographs that are part of the public collections of Rio de Janeiro. We start with an investigation of the presence of optical devices in nineteenth century Brazil, especially in the city of Rio
Maria Cristina Miranda da Silva
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

La importancia de la mirada en el comportamiento artístico: identidad histórica y percepción visual The importance of viewing in artistic behaviour: historical identity and visual perception

open access: yesAisthesis, 2011
Es evidente que hoy en día adquiere una importancia singular la visualización de imágenes y también la forma en que ellas -querámoslo o no- impactan nuestra retina, lo cual supone por parte del espectador unos criterios interpretativos que muchas veces ...
Carmen Porta
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Observer-based numerical schemes

open access: yes
Numerical analysis and control theory are fundamental areas in engineering and applied mathematics. This thesis explores three concepts from control theory used to enhance classical numerical solvers.
AMA Al Hayzea (22000814)
core   +3 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

The Observer

open access: yes, 2015
The official newspaper of Stern College for Women and Sy Syms School of BusinessFounded by the women of Yeshiva University's Stern College in 1958, The Observer is the official newspaper representing the student body of Stern College and Yeshiva ...
Kook, Elana (Editor)
core  

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