Results 131 to 140 of about 554,337 (247)

Deep Learning-Based Quantification of Spontaneous Pain Behaviours in Mice. [PDF]

Eur J Pain
Zanoletti M, Bellantoni E, Pombo Gomes L, Quadros Dos Santos ML, Souza Monteiro de Araújo D, De Siena G, Qader Kudsi S, Nassini R, Laurino M, De Logu F.   +9 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

AI-Assisted Scoring Improves Interobserver Agreement in Breast Cancer Biomarker Evaluation. [PDF]

Cancers (Basel)
Solass W, Desteffani C, Kalberer F, Scattolo B, Zagrapan B, Mulkern D, Caie P, Wartenberg M, Zlobec I, Lodge M.   +9 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Inter-observer reliability of osteoporotic fracture classification across imaging modalities for thoracolumbar osteoporotic fractures. [PDF]

Asian Spine J
Kalantari T, Zamarron A, Royuela A, Bello V, Aly MM, Gutiérrez-González R.   +5 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

[The Observer]

, 1964
Purim supplement for The Observer February 25 ...

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Error Injection in Task-Based Image Quality Pipelines: What Regression Testing Cannot Catch, and Why Neither Internal Identities nor Closed-Form References Suffice Alone. [PDF]

J Imaging
Yamamoto S.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The YU Observer

, 2012
The official newspaper of Stern College for Women and the Sy Syms School of BusinessFounded by the women of Yeshiva University's Stern College In 1953, The Observer Is the official newspaper representing the student body of Stern College and ...

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